Condensation of diamines with 2-phenyl-1,2,3-triazole-4-carboxaldehyde, quinoxaline-2-car- boxaldehyde or 2-(4-bromophenyl)-1,2,3-triazole-4-carboxaldehyde in the presence of glacial acetic acid gave a series of new bis-Schiff bases 5a～5d, 6a～6d and 7a～7d. The structures of new compounds were confirmed by elemental analysis, IR, 1H NMR, mass spectra and X-ary diffraction methods. The crystal of the compound 6c belongs to monoclinic, space group C2/c with cell parameters a＝1.7670(4) nm, b＝0.48001(10) nm, c＝1.1751(2) nm, α＝90.00°, β＝94.42(3)°, γ＝90.00°, V＝0.9937(4) nm3, Dc＝1.399 g/cm3, Z＝2, F(000)＝436, μ＝0.089 mm－1, R＝0.0413, wR＝0.1067. The preliminary biological activity tests show that the compound 6b has antiherpes virus type I activity toward Vero cells.

Key words: 2-phenyl-1,2,3-triazole-4-carboxaldehyde, bis-Schiff base, crystal structure, biological activity, quinoxaline-2-carboxaldehyde