Chin. J. Org. Chem. ›› 2010, Vol. 30 ›› Issue (12): 1854-1859. Previous Articles     Next Articles

Full Papers

三组分一锅法合成新型三唑及双三唑类化合物

雷鸣*,宋汪泽,詹祖金,陈小微,王彦广   

  1. (浙江大学化学系 杭州 310027)
  • 收稿日期:2010-02-11 修回日期:2010-05-18 发布日期:2010-07-05
  • 通讯作者: 雷鸣 E-mail:leiming@zju.edu.cn
  • 基金资助:

    缺电子炔烃参与的新串联反应研究

One-Pot Synthesis of Novel Triazol and Double Triazol Compounds

LEI Ming, SONG Wang-Ze, ZHAN Zu-Jin, CHEN Xiao-Wei, WANG Yan-Guang   

  1. (Department of Chemistry, Zhejiang University, Hangzhou 310027)
  • Received:2010-02-11 Revised:2010-05-18 Published:2010-07-05
  • Contact: Ming Lei E-mail:leiming@zju.edu.cn

An efficient one-pot method is used to prepare a series of 1,4-disubstituted-1,2,3-triazoles and double triazoles in water from a variety of Baylis-Hillman acetates, sodium azide and aromatic alkynes using CuCN as catalyst. This method is simple, efficient and base free.

Key words: one-pot synthesis, multicomponent reaction, 1,3-dipolar cycloaddition, 1,4-disubstituted- 1,2,3-triazole, double 1,4-disubstituted-1,2,3 triazole