Synthesis of N-Substituted Decahydroacridine-1,8-diones Promoted by Deep Eutectic Solvents

doi:10.6023/cjoc202003043

Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (9): 2988-2993.DOI: 10.6023/cjoc202003043 Previous Articles Next Articles

低共熔溶剂促进N-取代十氢吖啶-1,8-二酮类化合物的合成

肖立伟, 刘光仙, 李政, 任萍, 任丽磊, 孔洁

廊坊师范学院化学与材料科学学院河北廊坊 065000

收稿日期:2020-03-16 修回日期:2020-05-22 发布日期:2020-06-20
通讯作者: 肖立伟 E-mail:xiaoliwei@lfnu.edu.cn
基金资助:
河北省教育厅（Nos.ZD2020153，ZD2019036）和廊坊市科技局（No.2019011018）资助项目.

Synthesis of N-Substituted Decahydroacridine-1,8-diones Promoted by Deep Eutectic Solvents

Xiao Liwei, Liu Guangxian, Li Zheng, Ren Ping, Ren Lilei, Kong Jie

College of Chemistry and Material Science, Langfang Normal University, Langfang, Hebei 065000

Received:2020-03-16 Revised:2020-05-22 Published:2020-06-20
Supported by:
Project supported by the Educational Commission of Hebei Province (Nos. ZD2020153, ZD2019036) and the Science and Technology Bureau of Langfang City (No. 2019011018).

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Abstract

In the deep eutectic solvents (DES) consisted of choline chloride/zinc chloride(ChCl/ZnCl₂), a series of N-substi-tuted decahydroacridine-1,8-diones and decahydroacridine-1,8-diones were synthesized from diketones, aromatic aldehydes, ammonium acetates or aromatic amines with 75%~92% yields at 80~90 ℃ in 1~2 h. The advantages of the method are wild reaction condition, simple operation, short reaction time, high yield and friendly to environment.

Key words: deep eutectic solvent, decahydroacridine-1,8-diones, multicomponent reaction, green chemistry

Cite this article

Xiao Liwei, Liu Guangxian, Li Zheng, Ren Ping, Ren Lilei, Kong Jie. Synthesis of N-Substituted Decahydroacridine-1,8-diones Promoted by Deep Eutectic Solvents[J]. Chinese Journal of Organic Chemistry, 2020, 40(9): 2988-2993.

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低共熔溶剂促进N-取代十氢吖啶-1,8-二酮类化合物的合成

Synthesis of N-Substituted Decahydroacridine-1,8-diones Promoted by Deep Eutectic Solvents

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