Chin. J. Org. Chem. ›› 1992, Vol. 12 ›› Issue (3): 290-293. Previous Articles     Next Articles

Original Articles

聚合物支载的硼氢化钠还原剂系统对苯乙酮的不对称还原

钟建华;蒋济隆;陈家戚;徐章煌;吴敏   

  1. 湖北大学化学系
  • 发布日期:1992-06-25

The asymmetric reduction of acetophenone with polymer-supported borohydride reducing systems

ZHAONG JIANHUA;JIANG JILONG;CHEN JIAQI;XU ZHANGHUANG;WU MIN   

  • Published:1992-06-25

Reaction of ion exchange resin D151 with sodium borohydride in glyme at 65?gives polymer-supported reagent. The polymer-supported reagent reacts with chiral acids or alcs. to provide the polymer-supported reductants. Acetophenone was reduced by the reductants in rather low enantioselectivity (less than 30.1% of optical yield).

Key words: REDUCTION REACTION, ACETOPHENONE, REDUCER, SODIUM BOROHYDRIDE, ASYMMETRY, CHIRAL REAGENT, OPTICAL ACTIVITY

CLC Number: