Efficient N-Heterocyclic Carbene-Catalyzed Cascade Synthesis of Functionalized Naphthopyranone

doi:10.6023/cjoc201905034

Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (2): 470-477.DOI: 10.6023/cjoc201905034 Previous Articles Next Articles

氮杂环卡宾催化下官能化萘并吡喃酮的串联合成

李莎, 徐嘉煜, 罗鲜, 杨雯涵, 姚昌盛

江苏省功能材料绿色合成重点实验室江苏师范大学化学与材料科学学院徐州 221116

收稿日期:2019-05-14 修回日期:2019-09-19 发布日期:2019-10-09
通讯作者: 姚昌盛 E-mail:csyao@jsnu.edu.cn
基金资助:
国家自然科学基金（Nos.21871113，21372101）资助项目.

Efficient N-Heterocyclic Carbene-Catalyzed Cascade Synthesis of Functionalized Naphthopyranone

Li Sha, Xu Jiayu, Luo Xian, Yang Wenhan, Yao Changsheng

Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou 221116

Received:2019-05-14 Revised:2019-09-19 Published:2019-10-09
Supported by:
Project supported by the National Natural Science Foundation of China (Nos. 21871113, 21372101).

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Abstract

An efficient N-heterocyclic carbene (NHC)-catalyzed "Michael-Michael-Lactonization" cascade process involving chalcone derivatives and α-bromoenals for the syntheses of functionalized naphthopyranones was disclosed. This approach was qualified with good yields, readily available starting materials and mild reaction conditions.

Key words: N-heterocyclic carbene (NHC), α-bromoenals, chalcone derivatives, functionalized naphthopyranone, cascade reaction

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Li Sha, Xu Jiayu, Luo Xian, Yang Wenhan, Yao Changsheng. Efficient N-Heterocyclic Carbene-Catalyzed Cascade Synthesis of Functionalized Naphthopyranone[J]. Chinese Journal of Organic Chemistry, 2020, 40(2): 470-477.

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氮杂环卡宾催化下官能化萘并吡喃酮的串联合成

Efficient N-Heterocyclic Carbene-Catalyzed Cascade Synthesis of Functionalized Naphthopyranone

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