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化学学报
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化学学报 ›› 2002, Vol. 60 ›› Issue (3): 524-527. 上一篇    下一篇

研究论文

S-亚基谷胱甘肽对亚油酸过氧化和苯乙烯聚合的抑制作用的研究

金景;吴隆民;张自义   

  1. 兰州大学,兰州(730000)
  • 发布日期:2002-03-15

Inhibition Effect of S-Nitrosoglutathione on Linoleic Acid Peroxidation and on Styrene Polymerization

Jin Jing;Wu Longmin;Zhang Ziyi   

  1. National Laboratory of Applied Organic Chemistry, Lanzhou University,Lanzhou(730000)
  • Published:2002-03-15

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研究了S－亚硝基谷胱甘肽（GSNO）对偶氮二异丁腈(AIBN)引发亚油酸过氧化 和苯乙烯聚合的抑制作用。GSNO的抑制作用可能归结为反应中生砀氮氧自由基的抑 制活性。EPR证据表明，含有AIBN和GSNO的DMSO溶液在无氧和50 ℃下，生成了谷胱 甘肽巯基，2－氰基－2－丙基氮氧自由基。

关键词: 谷胱甘肽, 阻聚, 抑制剂, 亚油酸, 苯乙烯, 聚合, 顺磁共振

S-Nitrosoglutathione (GSNO) exhibits inhibition effect on linoleic acid peroxidation and on styrene polymerization, using 2,2'- azobisisbutylnitrile (AIBN) as the initiator. Heating a solution of GSNO and AIBN in DMSO under argon produced an EPR signal, which was attributed to glutathiyl 2-cyano-2-propyl aminoxyl radical by comparison with the EPR spectrum obtained with a solution of NO and AIBN under the same experimental conditions. The results suggested that GSNO was converted to an aminoxyl radical and acted as such in the inhibition experiments.

Key words: GLUTATHIONE, RETARDATION, INHIBITOR, LINOLEIC ACID, STYRENE, POLYMERIZATION, PR

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