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化学学报
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化学学报 ›› 1995, Vol. 53 ›› Issue (8): 769-774. 上一篇    下一篇

研究论文

Cu(II)-氨基酸-核苷酸三元配合物 II: Cu(II)-L-组氨酸、L-赖氨酸－5'-嘌呤核苷酸三元配合物

邵昌平;赵丽华;刘宇新;郭和夫   

  1. 中国科学院大连化学物理研究所
  • 发布日期:1995-08-15

Ternary complexes of copper(II) with amino acid and nucleotide

SHAO CHANGPING;ZHAO LIHUA;LIU YUXIN;GUO HEFU   

  • Published:1995-08-15

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合成和表征了新的三元配合物: [Cu(L-His)(5'-AMP)]Cl2.4H2O,[Cu(L-His)(5'-GMP)]Cl2, [Cu(L-His)(5'-IMP)]Cl2.2H2O,[Cu(l-Lys)2(5'-GMP)]Cl2.6H2O, Na2[Cu(L-Lys)2(5'-GMPH_2)].6H2O,Na2[Cu(L-Lys)2(5'-GTPH_2)].6H2O, Na2[Cu(L-Lys)2(5'-IMPH_2)].10H2O. IR及NMR谱表明, 5'-嘌呤核苷酸以嘌呤碱基上的7-N原子与Cu(II)配位。在5'-嘌呤核苷酸形成的配合物中, 磷酸根不参与配位, 但是Na2.5'-GMPH-2和Na.5'-GTPH-2的磷酸根参与配位, 而Na2.5'-IMPH-2的磷酸根不参与配位。

关键词: 氨基酸, 红外分光光度法, 元素分析, 核磁共振谱法, 赖氨酸, 铜络合物, 三元络合物, 组氨酸, 核苷酸, 嘌呤核苷酸

The ternary complexes of copper(II) with amino acid (L-His and L-Lys) and nucleotide (5'-purine nucleotide and its salt of sodium) were first synthesized and characterized by elemental, conductivity, IR, ^1H NMR and ^1^3C NMR spectra. In the ternary complexes, the purine base coordinates with copper(II) through the 7-N atom. The phosphate group of 5'-nucleotide in the ternary complexes does not coordinate with copper(II). When the nucleotide takes part in the reaction in the form of Na2.5'-GMPH_2 and Na2.5'-GTPH_2, the phosphate group may be coordinate with copper(II) in the ternary complexes, but not for Na2.5'-IMPH_2.

Key words: AMINO ACID, INFRARED SPECTROPHOTOMETRY, ELEMENTAL ANALYSIS, NMR SPECTROMETRY, LYSINE, COPPER COMPLEX, TERNARY COMPLEX, HISTIDINE, NUCLEOTIDES

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