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化学学报
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化学学报 ›› 1991, Vol. 49 ›› Issue (7): 723-728. 上一篇    

所属专题： 纪念南开大学化学学科创建100周年

研究论文

三丁基锡羧酸酯的结构表征及其生物活性研究

谢庆兰;李树正;张素华;张殿坤;张招贵;胡锦民   

  1. 南开大学元素有机化学研究所;江西大学化学系
  • 发布日期:1991-07-15

The structure and biological activity of tributyltin carboxylates

XIE QINGLAN;LI SHUZHENG;ZHANG SUHUA;ZHANG DIANKUN;ZHANG ZHAOGUI;HU JINMIN   

  • Published:1991-07-15

PDF

636

被引次数

52

合成了三十个三丁基锡羧酸酯Bu3SnO2CR(R=烷基、芳基、芳氧甲基和呋喃基)。通过对它们的红外光谱、核磁共振谱(^1^3C, ^1^1^9Sn)的研究, 表明羰基红外吸收频率与锡原子的配位数有密切关系, 同样分子上的微小变化明显地表现在δ119Sn上, 对位取代基苯甲酸酯的δ119Sn与苯环上取代基的Hammett常数(σ)之间存在良好的线性关系:δ119Sn=19.11σ+110.612 n=7, γ=0.9955着重研究了部分化合物在经济作物上的抗病原菌能力, 结果表明, 这是一类具有广谱性的有机锡化合物, 抗菌活性优于对比药剂朴海因, 接近或相当于多菌灵, 它们同时具有较强的除草活性。

关键词: 红外分光光度法, 核磁共振谱法, 羧酸酯, 结构分析, 锡化合物, 除草剂, 丁烷 P, 抗菌性

Thirty tributyltin carboxylates were synthesized using (Bu3Sn)2O as a precursor. The structures were studied by IR and NMR. The absorption frequencies of the carbonyl group markedly depended on the coordination no. of the tin atom. The chem. shifts of 119Sn and 13C and the 1J(119Sn-13Sn) coupling constants of the compounds were determine Small structural changes around the tin atom were reflected in the 119Sn chem. shifts. For tributyltin arylcarboxylates, a relationship between 119Sn chem. shifts and Hammett constants of the para-substituents was found. The biol. activities of same compounds have been studied. They may be used as fungicides for fruit.

Key words: INFRARED SPECTROPHOTOMETRY, NMR SPECTROMETRY, CARBOXYLIC ACID ESTER, STRUCTURAL ANALYSIS, TIN COMPOUND, HERBICIDES, BUTANE P, ANTIBIOTIC PROPERTY

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