Transition Metal-Catalyzed C—H Trifluoromethylation

doi:10.6023/A12040135

Acta Chimica Sinica ›› 2012, Vol. 70 ›› Issue (16): 1679-1681.DOI: 10.6023/A12040135 Previous Articles Next Articles

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过渡金属催化碳氢键三氟甲基化

潘菲^a, 施章杰^a,b

a 北京分子科学国家实验室北京大学化学与分子工程学院生物有机与分子工程教育部重点实验室北京 100871;
b 中国科学院上海有机化学研究所金属有机化学国家重点实验室上海 200032

投稿日期:2012-07-30 发布日期:2012-08-15
通讯作者: 施章杰 E-mail:zshi@pku.edu.cn
基金资助:
项目受科技部973计划(No. 2009CB825300)和国家自然科学基金(Nos. 20925207, 21002001)资助.

Transition Metal-Catalyzed C—H Trifluoromethylation

Pan Fei^a, Shi Zhangjie^a,b

a Beijing National Laboratory of Molecular Science (BNLMS, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China;
b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Received:2012-07-30 Published:2012-08-15
Supported by:
Project supported by the “973” Project from the Ministry of Science and Technology of the People’s Republic of China (No. 2009CB825300) and National Natural Science Foundation of China (Nos. 20925207, 21002001).

In recent years, transition metal-catalyzed C—H trifluoromethylation has been well developed, which is mainly focused on the terminal alkyne C(sp)—H, aromatic and heterocyclic C(sp²)—H and allylic C(sp³)—H trifluoromethylation. This paper briefly overviews the latest developments in this field, the characteristics of various types of reaction, as well as the facing challenges and future direction.

Key words: transition metal, catalysis, trifluoromethylation, C—H activation, directing, cross-coupling

Cite this article

Pan Fei, Shi Zhangjie. Transition Metal-Catalyzed C—H Trifluoromethylation[J]. Acta Chimica Sinica, 2012, 70(16): 1679-1681.

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过渡金属催化碳氢键三氟甲基化

Transition Metal-Catalyzed C—H Trifluoromethylation

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