Near-Infrared-II Fluorescence Probes Based on Organic Small Molecules

doi:10.6023/A20050190

Acta Chimica Sinica ›› 2020, Vol. 78 ›› Issue (9): 901-915.DOI: 10.6023/A20050190 Previous Articles Next Articles

Special Issue: 分子探针、纳米生物学与生命分析化学

Review

近红外二区有机小分子荧光探针

桑若愚^a, 许兴鹏^a, 王其^a,b, 范曲立^a, 黄维^c

a 南京邮电大学有机电子与信息显示国家重点实验室培育基地信息材料与纳米技术研究院南京 210023;
b 东南大学生物电子学国家重点实验室南京 210096;
c 西北工业大学柔性电子研究院西安 710072

投稿日期:2020-05-28 发布日期:2020-07-15
通讯作者: 王其, 范曲立 E-mail:iamqwang@njupt.edu.cn;iamqlfan@njupt.edu.cn
作者简介:桑若愚,男,汉族,1996年出生于湖南,2019年本科毕业于河北大学,随后加入南京邮电大学范曲立课题组攻读硕士学位,研究方向为基于NIR-II荧光成像的肿瘤诊疗研究;许兴鹏,男,汉族,1995年出生于安徽,2019年本科毕业于淮北师范大学,随后加入南京邮电大学范曲立课题组攻读硕士学位,研究方向为肿瘤光学诊疗一体化;王其,南京邮电大学副教授,2015年博士毕业于南京大学,同年进入南京邮电大学材料科学与工程学院工作.目前主要从事新型有机小分子NIR-II荧光探针的设计、合成及其在肿瘤诊疗领域的应用研究;范曲立,南京邮电大学教授,2003年于新加坡国立大学获得博士学位,2003年至2006年在复旦大学工作,2006年8月起就职于南京邮电大学.主要研究方向是面向纳米生物医学领域有机半导体材料的制备与临床前的应用研究,近五年来以第一或通讯作者在Nature Communications、Journal of the American Chemical Society、Advanced Materials、ACS Nano等国际期刊发表SCI论文80余篇;承担和参与国家、省部级各类项目10余项,2012年获国家优秀青年科学基金,2013年获国家自然科学二等奖(排名第四),2014年入选国家"百千万人才工程",2019年入选国家"万人计划"中青年科技创新领军人才;黄维,教授,博导,有机电子、塑料电子、印刷电子、生物电子及柔性电子学家,中国科学院院士、俄罗斯科学院外籍院士、亚太材料科学院院士、东盟工程与技术科学院外籍院士、巴基斯坦科学院外籍院士.历任复旦大学先进材料研究院院长,南京邮电大学副校长、党委常委,南京工业大学校长、党委副书记,2017任西北工业大学党委常委、常务副校长.曾两次获得国家自然科学奖二等奖、三次获得高等学校科学研究优秀成果奖(科学技术)自然科学奖一等奖、多次获得江苏省科学技术奖一等奖和二等奖,以及何梁何利基金"科学与技术进步奖".
基金资助:
项目受国家自然科学基金（Nos.21602112，21674048）及东南大学生物电子学国家重点实验室开放研究基金资助课题（No.OPSKLB202006）资助.

Near-Infrared-II Fluorescence Probes Based on Organic Small Molecules

Sang Ruoyu^a, Xu Xingpeng^a, Wang Qi^a,b, Fan Quli^a, Huang Wei^c

a Key Laboratory for Organic Electronics and Information Displays, Institute of Advanced Materials, Nanjing University of Posts & Telecommunications, Nanjing 210023, China;
b State Key Laboratory of Bioelectronics, Southeast University, Nanjing 210096, China;
c Institute of Flexible Electronics, Northwestern Polytechnical University, Xi'an 710072, China

Received:2020-05-28 Published:2020-07-15
Supported by:
Project supported by the National Natural Science Foundation of China (Nos. 21602112, 21674048) and the Open Research Fund of State Key Laboratory of Bioelectronics, Southeast University (No. OPSKLB202006).

Fluorescence imaging plays an important role in the diagnosis and treatment of major diseases by virtue of its high sensitivity, strong specificity and excellent spatio-temporal resolution. However, traditional near-infrared-I (NIR-I, 700~900 nm) fluorescence imaging often encounters multiple concerns such as poor tissue penetration, which limits its clinical application. In recent years, near-infrared-II (NIR-II, 1000~1700 nm) fluorescence imaging has been proven to provide better imaging qualities, higher signal-to-noise ratio and deeper tissue penetration than those observed in the NIR-I window due to the diminished photon scattering and tissue auto-fluorescence. Among NIR-II fluorescent probes, organic small molecules are becoming research hotspots in this field due to their advantages of low toxicity, simple structure and fast metabolism. This review describes the recent progress in the design of organic small molecule NIR-II probes and the strategies for improving the fluorescence quantum yield. The application of small molecule NIR-II probes in activatable imaging, multimode imaging and theranostics are evaluated systematically. Current challenges and future perspectives in this emerging field are also prospected.

Key words: near-infrared-II fluorescence imaging, organic small molecules, activatable probe, multimodal imaging, phototherapy

Cite this article

Sang Ruoyu, Xu Xingpeng, Wang Qi, Fan Quli, Huang Wei. Near-Infrared-II Fluorescence Probes Based on Organic Small Molecules[J]. Acta Chimica Sinica, 2020, 78(9): 901-915.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

share this article

References

[1] (a) Cai, Y.; Wei, Z.; Song, C.; Tang, C.; Han, W.; Dong, X. Chem. Soc. Rev. 2019, 48, 22.
(b) Yan, P.; Wang, T.; Zhang, D.; Ma, X. Chin. J. Org. Chem. 2019, 39, 916(in Chinese). (闫沛沛, 王婷, 张丹, 马晓雪, 有机化学, 2019, 39, 916.)
(c) Xiong, L.; Fan, Y.; Zhang, F. Acta Chim. Sinica 2019, 77, 1239(in Chinese). (熊麟, 凡勇, 张凡, 化学学报, 2019, 77, 1239.)
(d) Yang, L.; Liu, B.; Li, N.; Tang, B. Acta Chim. Sinica 2017, 75, 1047(in Chinese). (杨立敏, 刘波, 李娜, 唐波, 化学学报, 2017, 75, 1047.)
[2] Zhu, S.; Tian, R.; Antaris, A. L.; Chen, X.; Dai, H. Adv. Mater. 2019, 31, 1900321.
[3] (a) He, S.; Song, J.; Qu, J.; Cheng, Z. Chem. Soc. Rev. 2018, 47, 4258.
(b) Li, C.; Wang, Q. ACS Nano 2018, 12, 9654.
(c) Tao, Z.; Hong, G.; Shinji, C.; Chen, C.; Diao, S.; Antaris, A. L.; Zhang, B.; Zou, Y.; Dai, H. Angew. Chem. Int. Ed. 2013, 52, 13002.
(d) Luo, X.; Chen, M.; Yang, Q. Acta Chim. Sinica 2020, 78, 373(in Chinese). (罗兴蕊, 陈敏文, 杨晴来, 化学学报, 2020, 78, 373.)
[4] (a) Song, C.; Zhang, Y.; Li, C.; Chen, G.; Kang, X.; Wang, Q. Adv. Funct. Mater. 2016, 26, 4192.
(b) Yang, T.; Tang, Y. a.; Liu, L.; Lv, X.; Wang, Q.; Ke, H.; Deng, Y.; Yang, H.; Yang, X.; Liu, G.; Zhao, Y.; Chen, H. ACS Nano 2017, 11, 1848.
(c) Ma, Z.; Zhang, M.; Yue, J.; Alcazar, C.; Zhong, Y.; Doyle, T. C.; Dai, H.; Huang, N. F. Adv. Funct. Mater. 2018, 28, 1803417.
(d) Xu, Y.; Zhao, Y.; Zhang, Y.; Cui, Z.; Wang, L.; Fan, C.; Gao, J.; Sun, Y. Acta Chim. Sinica 2018, 76, 393(in Chinese). (徐毅, 赵彦, 张叶俊, 崔之芬, 王丽华, 樊春海, 高基民, 孙艳红, 化学学报, 2018, 76, 393.)
[5] (a) Naczynski, D. J.; Tan, M. C.; Zevon, M.; Wall, B.; Kohl, J.; Kulesa, A.; Chen, S.; Roth, C. M.; Riman, R. E.; Moghe, P. V. Nat. Commun. 2013, 4, 2199.
(b) Kamimura, M.; Kanayama, N.; Tokuzen, K.; Soga, K.; Nagasaki, Y. Nanoscale 2011, 3, 3705.
(c) Shao, W.; Chen, G.; Kuzmin, A.; Kutscher, H. L.; Pliss, A.; Ohulchanskyy, T. Y.; Prasad, P. N. J. Am. Chem. Soc. 2016, 138, 16192.
[6] (a) Hong, G.; Diao, S.; Antaris, A. L.; Dai, H. Chem. Rev. 2015, 115, 10816.
(b) Hong, G.; Lee, J. C.; Robinson, J. T.; Raaz, U.; Xie, L.; Huang, N. F.; Cooke, J. P.; Dai, H. Nat. Med. 2012, 18, 1841.
(c) Robinson, J. T.; Hong, G.; Liang, Y.; Zhang, B.; Yaghi, O. K.; Dai, H. J. Am. Chem. Soc. 2012, 134, 10664.
[7] Wu, C.; Huang, X.; Tang, Y.; Xiao, W.; Sun, L.; Shao, J.; Dong, X. Chem. Commun. 2019, 55, 790.
[8] Peng, F.; Setyawati, M. I.; Tee, J. K.; Ding, X.; Wang, J.; Nga, M. E.; Ho, H. K.; Leong, D. T. Nat. Nanotechnol. 2019, 14, 279.
[9] Kenry; Duan, Y.; Liu, B. Adv. Mater. 2018, 30, 1802394.
[10] Antaris, A. L.; Chen, H.; Cheng, K.; Sun, Y.; Hong, G.; Qu, C.; Diao, S.; Deng, Z.; Hu, X.; Zhang, B.; Zhang, X.; Yaghi, O. K.; Alamparambil, Z. R.; Hong, X.; Cheng, Z.; Dai, H. Nat. Mater. 2016, 15, 235.
[11] Antaris, A. L.; Chen, H.; Diao, S.; Ma, Z.; Zhang, Z.; Zhu, S.; Wang, J.; Lozano, A. X.; Fan, Q.; Chew, L.; Zhu, M.; Cheng, K.; Hong, X.; Dai, H.; Cheng, Z. Nat. Commun. 2017, 8, 15269.
[12] Feng, Y.; Zhu, S.; Antaris, A. L.; Chen, H.; Xiao, Y.; Lu, X.; Jiang, L.; Diao, S.; Yu, K.; Wang, Y.; Herraiz, S.; Yue, J.; Hong, X.; Hong, G.; Cheng, Z.; Dai, H.; Hsueh, A. J. Chem. Sci. 2017, 8, 3703.
[13] Ding, F.; Li, C.; Xu, Y.; Li, J.; Li, H.; Yang, G.; Sun, Y. Adv. Healthc. Mater. 2018, 7, 1800973.
[14] Yi, W.; Zhou, H.; Li, A.; Yuan, Y.; Guo, Y.; Li, P.; Qi, B.; Xiao, Y.; Yu, A.; Hu, X. Biomater. Sci. 2019, 7, 1043.
[15] Sun, Y.; Qu, C.; Chen, H.; He, M.; Tang, C.; Shou, K.; Hong, S.; Yang, M.; Jiang, Y.; Ding, B.; Xiao, Y.; Xing, L.; Hong, X.; Cheng, Z. Chem. Sci. 2016, 7, 6203.
[16] Sun, Y.; Ding, M.; Zeng, X.; Xiao, Y.; Wu, H.; Zhou, H.; Ding, B.; Qu, C.; Hou, W.; Er-bu, A. G. A.; Zhang, Y.; Cheng, Z.; Hong, X. Chem. Sci. 2017, 8, 3489.
[17] Zeng, X.; Xue, L.; Chen, D.; Li, S.; Nong, J.; Wang, B.; Tang, L.; Li, Q.; Li, Y.; Deng, Z.; Hong, X.; Wu, M.; Xiao, Y. Chem. Commun. 2019, 55, 14287.
[18] Zhou, H.; Li, S.; Zeng, X.; Zhang, M.; Tang, L.; Li, Q.; Chen, D.; Meng, X.; Hong, X. Chin. Chem. Lett. 2020, 31, 1382.
[19] Zhang, X.-D.; Wang, H.; Antaris, A. L.; Li, L.; Diao, S.; Ma, R.; Nguyen, A.; Hong, G.; Ma, Z.; Wang, J.; Zhu, S.; Castellano, J. M.; Wyss-Coray, T.; Liang, Y.; Luo, J.; Dai, H. Adv. Mater. 2016, 28, 6872.
[20] Yang, Q.; Ma, Z.; Wang, H.; Zhou, B.; Zhu, S.; Zhong, Y.; Wang, J.; Wan, H.; Antaris, A.; Ma, R.; Zhang, X.; Yang, J.; Zhang, X.; Sun, H.; Liu, W.; Liang, Y.; Dai, H. Adv. Mater. 2017, 29, 1605497.
[21] Yang, Q.; Hu, Z.; Zhu, S.; Ma, R.; Ma, H.; Ma, Z.; Wan, H.; Zhu, T.; Jiang, Z.; Liu, W.; Jiao, L.; Sun, H.; Liang, Y.; Dai, H. J. Am. Chem. Soc. 2018, 140, 1715.
[22] Ma, H.; Liu, C.; Hu, Z.; Yu, P.; Zhu, X.; Ma, R.; Sun, Z.; Zhang, C.-H.; Sun, H.; Zhu, S.; Liang, Y. Chem. Mater. 2020, 32, 2061.
[23] (a) Luo, J.; Xie, Z.; Lam, J. W. Y.; Cheng, L.; Chen, H.; Qiu, C.; Kwok, H. S.; Zhan, X.; Liu, Y.; Zhu, D.; Tang, B. Z. Chem. Commun. 2001, 1740.
(b) Zhu, C.; Kwok, R. T. K.; Lam, J. W. Y.; Tang, B. Z. ACS Appl. Bio Mater. 2018, 1, 1768.
(c) Gao, Y.; Zhang, H.; He, Z.; Fang, F.; Wang, C.; Zeng, K.; Gao, S.; Meng, F.; Luo, L.; Tang, B. Z. Mater. Chem. Front. 2020, 4, 1623.
[24] Sheng, Z.; Guo, B.; Hu, D.; Xu, S.; Wu, W.; Liew, W. H.; Yao, K.; Jiang, J.; Liu, C.; Zheng, H.; Liu, B. Adv. Mater. 2018, 30, 1800766.
[25] Lin, J.; Zeng, X.; Xiao, Y.; Tang, L.; Nong, J.; Liu, Y.; Zhou, H.; Ding, B.; Xu, F.; Tong, H.; Deng, Z.; Hong, X. Chem. Sci. 2019, 10, 1219.
[26] Liu, S.; Chen, C.; Li, Y.; Zhang, H.; Liu, J.; Wang, R.; Wong, S. T. H.; Lam, J. W. Y.; Ding, D.; Tang, B. Z. Adv. Funct. Mater. 2019, 30, 1908125.
[27] Wu, W.; Yang, Y.; Yang, Y.; Yang, Y.; Zhang, K.; Guo, L.; Ge, H.; Chen, X.; Liu, J.; Feng, H. Small 2019, 15, 1805549.
[28] Li, Q.; Ding, Q.; Li, Y.; Zeng, X.; Liu, Y.; Lu, S.; Zhou, H.; Wang, X.; Wu, J.; Meng, X.; Deng, Z.; Xiao, Y. Chem. Commun. 2020, 56, 3289.
[29] Li, Y.; Liu, Y.; Li, Q.; Zeng, X.; Tian, T.; Zhou, W.; Cui, Y.; Wang, X.; Cheng, X.; Ding, Q.; Wang, X.; Wu, J.; Deng, H.; Li, Y.; Meng, X.; Deng, Z.; Hong, X.; Xiao, Y. Chem. Sci. 2020, 11, 2621.
[30] Li, Y.; Cai, Z.; Liu, S.; Zhang, H.; Wong, S. T. H.; Lam, J. W. Y.; Kwok, R. T. K.; Qian, J.; Tang, B. Z. Nat. Commun. 2020, 11, 1255.
[31] Starosolski, Z.; Bhavane, R.; Ghaghada, K. B.; Vasudevan, S. A.; Kaay, A.; Annapragada, A. PLOS ONE 2017, 12, 0187563.
[32] Suo, Y.; Wu, F.; Xu, P.; Shi, H.; Wang, T.; Liu, H.; Cheng, Z. Adv. Healthc. Mater. 2019, 8, 1900974.
[33] Hu, Z.; Fang, C.; Li, B.; Zhang, Z.; Cao, C.; Cai, M.; Su, S.; Sun, X.; Shi, X.; Li, C.; Zhou, T.; Zhang, Y.; Chi, C.; He, P.; Xia, X.; Chen, Y.; Gambhir, S. S.; Cheng, Z.; Tian, J. Nat. Biomed. Eng. 2020, 4, 259.
[34] Cosco, E. D.; Caram, J. R.; Bruns, O. T.; Franke, D.; Day, R. A.; Farr, E. P.; Bawendi, M. G.; Sletten, E. M. Angew. Chem. Int. Ed. 2017, 56, 13126.
[35] Li, B.; Lu, L.; Zhao, M.; Lei, Z.; Zhang, F. Angew. Chem. Int. Ed. 2018, 57, 7483.
[36] Sun, C.; Li, B.; Zhao, M.; Wang, S.; Lei, Z.; Lu, L.; Zhang, H.; Feng, L.; Dou, C.; Yin, D.; Xu, H.; Cheng, Y.; Zhang, F. J. Am. Chem. Soc. 2019, 141, 19221.
[37] Ding, B.; Xiao, Y.; Zhou, H.; Zhang, X.; Qu, C.; Xu, F.; Deng, Z.; Cheng, Z.; Hong, X. J. Med. Chem. 2019, 62, 2049.
[38] Lei, Z.; Li, X.; Luo, X.; He, H.; Zheng, J.; Qian, X.; Yang, Y. Angew. Chem. Int. Ed. 2017, 56, 2979.
[39] Sun, P.; Wu, Q.; Sun, X.; Miao, H.; Deng, W.; Zhang, W.; Fan, Q.; Huang, W. Chem. Commun. 2018, 54, 13395.
[40] Bai, L.; Sun, P.; Liu, Y.; Zhang, H.; Hu, W.; Zhang, W.; Liu, Z.; Fan, Q.; Li, L.; Huang, W. Chem. Commun. 2019, 55, 10920.
[41] (a) Li, C.; Li, W.; Liu, H.; Zhang, Y.; Chen, G.; Li, Z.; Wang, Q. Angew. Chem. Int. Ed. 2020, 59, 247.
(b) Zhu, J.; Zhang, H.; Liu, M.; Liu, J.; Liao, Y.; Quan, Z.; Wang, X. Chin. J. Org. Chem. 2020, 40, 1043(in Chinese). (朱继华, 张浩, 刘敏, 刘旌江, 廖原, 权正军, 王喜存, 有机化学, 2020, 40, 1043.)
(c) Yan, M.; Peng, W.; Wang, H.; Zhang, D.; Li, Z. Chin. J. Org. Chem. 2019, 39, 2567(in Chinese). (闫萌, 彭文昶, 王辉, 张丹维, 黎占亭, 有机化学, 2019, 39, 2567.)
(d) Cheng, P.; Pu, K. ACS Appl. Mater. Interfaces 2020, 12, 5286.
[42] Tang, Y.; Pei, F.; Lu, X.; Fan, Q.; Huang, W. Adv. Opt. Mater. 2019, 7, 1900917.
[43] Gao, P.; Pan, W.; Li, N.; Tang, B. Chem. Sci. 2019, 10, 6035.
[44] Jiao, C.; Liu, Y.; Lu, W.; Zhang, P.; Wang, Y. Chin. J. Org. Chem. 2019, 39, 591(in Chinese). (矫春鹏, 刘媛媛, 路文娟, 张平平, 王延风, 有机化学, 2019, 39, 591.)
[45] Lou, Z.; Li, P.; Han, K. Acc. Chem. Res. 2015, 48, 1358.
[46] Bray, F.; Ferlay, J.; Soerjomataram, I.; Siegel, R. L.; Torre, L. A.; Jemal, A. CA-Cancer J. Clin. 2018, 68, 394.
[47] Szabo, C.; Coletta, C.; Chao, C.; Módis, K.; Szczesny, B.; Papapetropoulos, A.; Hellmich, M. R. Proc. Natl. Acad. Sci. U. S. A. 2013, 201306241.
[48] Xu, G.; Yan, Q. L.; Lv, X. G.; Zhu, Y.; Xin, K.; Shi, B.; Wang, R. C.; Chen, J.; Gao, W.; Shi, P.; Fan, C. H.; Zhao, C. C.; Tian, H. Angew. Chem. Int. Ed. 2018, 57, 3626.
[49] Shi, B.; Yan, Q.; Tang, J.; Xin, K.; Zhang, J.; Zhu, Y.; Xu, G.; Wang, R.; Chen, J.; Gao, W.; Zhu, T.; Shi, J.; Fan, C.; Zhao, C.; Tian, H. Nano Lett. 2018, 18, 6411.
[50] Shi, B.; Ren, N.; Gu, L.; Xu, G.; Wang, R.; Zhu, T.; Zhu, Y.; Fan, C.; Zhao, C.; Tian, H. Angew. Chem. Int. Ed. 2019, 58, 16826.
[51] (a) Li, J.; Jiang, R.; Wang, Q.; Li, X.; Hu, X.; Yuan, Y.; Lu, X.; Wang, W.; Huang, W.; Fan, Q. Biomaterials 2019, 217, 119304.
(b) Zhang, X.; Tian, G.; Zhang, X.; Wang, Q.; Gu, Z. Acta Chim. Sinica 2019, 77, 406(in Chinese). (张晓蕾, 田甘, 张潇, 王清, 谷战军, 化学学报, 2019, 77, 406.)
[52] Tang, Y.; Li, Y.; Wang, Z.; Pei, F.; Hu, X.; Ji, Y.; Li, X.; Zhao, H.; Hu, W.; Lu, X.; Fan, Q.; Huang, W. Chem. Commun. 2019, 55, 27.
[53] Feng, W.; Zhang, Y.; Li, Z.; Zhai, S.; Lv, W.; Liu, Z. Anal. Chem. 2019, 91, 15757.
[54] Li, D.; Wang, S.; Lei, Z.; Sun, C.; El-Toni, A. M.; Alhoshan, M. S.; Fan, Y.; Zhang, F. Anal. Chem. 2019, 91, 4771.
[55] Lei, Z.; Sun, C.; Pei, P.; Wang, S.; Li, D.; Zhang, X.; Zhang, F. Angew. Chem. Int. Ed. 2019, 58, 8166.
[56] Yin, C.; Zhen, X.; Fan, Q.; Huang, W.; Pu, K. ACS Nano 2017, 11, 4174.
[57] Tang, Y.; Li, Y.; Lu, X.; Hu, X.; Zhao, H.; Hu, W.; Lu, F.; Fan, Q.; Huang, W. Adv. Funct. Mater. 2019, 29, 1807376.
[58] Ge, X.; Lou, Y.; Su, L.; Chen, B.; Guo, Z.; Gao, S.; Zhang, W.; Chen, T.; Song, J.; Yang, H. Anal. Chem. 2020, 92, 6111.
[59] Wang, S.; Fan, Y.; Li, D.; Sun, C.; Lei, Z.; Lu, L.; Wang, T.; Zhang, F. Nat. Commun. 2019, 10, 1058.
[60] Li, J.; Yuan, Y.; Zeng, G. S.; Li, X.; Yang, Z.; Li, X. Z.; Jiang, R. C.; Hu, W. B.; Sun, P. F.; Wang, Q.; Lu, X. M.; Fan, Q. L.; Huang, W. Polym. Chem. 2016, 7, 6890.
[61] Brown, J. M.; Wilson, W. R. Nat. Rev. Cancer 2004, 4, 437.
[62] Meng, X.; Zhang, J.; Sun, Z.; Zhou, L.; Deng, G.; Li, S.; Li, W.; Gong, P.; Cai, L. Theranostics 2018, 8, 6025.
[63] Ouyang, J.; Sun, L.; Zeng, Z.; Zeng, C.; Zeng, F.; Wu, S. Angew. Chem. Int. Ed. 2020, 59, 10111.
[64] Dou, K.; Huang, W.; Xiang, Y.; Li, S.; Liu, Z. Anal. Chem. 2020, 92, 4177.

[65] (a) Mou, J.; Lin, T.; Huang, F.; Chen, H.; Shi, J. Biomaterials 2016, 84, 13.
(b) Li, J.; Rao, J.; Pu, K. Biomaterials 2018, 155, 217.
[66] Feng, G.; Liu, B. Small 2016, 12, 6528.
[67] Sun, Y.; Zeng, X.; Xiao, Y.; Liu, C.; Zhu, H.; Zhou, H.; Chen, Z.; Xu, F.; Wang, J.; Zhu, M.; Wu, J.; Tian, M.; Zhang, H.; Deng, Z.; Cheng, Z.; Hong, X. Chem. Sci. 2018, 9, 2092.
[68] Zhang, Q.; Zhou, H.; Chen, H.; Zhang, X.; He, S.; Ma, L.; Qu, C.; Fang, W.; Han, Y.; Wang, D.; Huang, Y.; Sun, Y.; Fan, Q.; Chen, Y.; Cheng, Z. Small 2019, 15, 1903382.
[69] Zhou, H.; Yang, H.; Tang, L.; Wang, Y.; Li, Y.; Liu, N.; Zeng, X.; Yan, Y.; Wu, J.; Chen, S.; Xiao, L.; Yu, Y.; Deng, Z.; Deng, H.; Hong, X.; Xiao, Y. J. Mater. Chem. C 2019, 7, 9448.
[70] Chen, C.; Ou, H.; Liu, R.; Ding, D. Adv. Mater. 2019, 31, 1806331.
[71] Cheng, K.; Chen, H.; Jenkins, C. H.; Zhang, G.; Zhao, W.; Zhang, Z.; Han, F.; Fung, J.; Yang, M.; Jiang, Y.; Xing, L.; Cheng, Z. ACS Nano 2017, 11, 12276.
[72] Zhang, R.; Xu, Y.; Zhang, Y.; Kim, H. S.; Sharma, A.; Gao, J.; Yang, G.; Kim, J. S.; Sun, Y. Chem. Sci. 2019, 10, 8348.
[73] Zhang, R.; Wang, Z.; Xu, L.; Xu, Y.; Lin, Y.; Zhang, Y.; Sun, Y.; Yang, G. Anal. Chem. 2019, 91, 12476.
[74] Wang, Q.; Xia, B.; Xu, J.; Niu, X.; Cai, J.; Shen, Q.; Wang, W.; Huang, W.; Fan, Q. Mater. Chem. Front. 2019, 3, 650.
[75] Qi, J.; Li, J.; Liu, R.; Li, Q.; Zhang, H.; Lam, J. W. Y.; Kwok, R. T. K.; Liu, D.; Ding, D.; Tang, B. Z. Chem 2019, 5, 2657.
[76] (a) Wang, Q.; Zhang, P.; Xu, J.; Xia, B.; Tian, L.; Chen, J.; Li, J.; Lu, F.; Shen, Q.; Lu, X.; Huang, W.; Fan, Q. ACS Appl. Bio Mater. 2018, 1, 70.
(b) Wang, Q.; Tian, L.; Xu, J.; Xia, B.; Li, J.; Lu, F.; Lu, X.; Wang, W.; Huang, W.; Fan, Q. Chem. Commun. 2018, 54, 10328.
[77] (a) Dai, Y.; Su, J.; Wu, K.; Ma, W.; Wang, B.; Li, M.; Sun, P.; Shen, Q.; Wang, Q.; Fan, Q. ACS Appl. Mater. Interfaces 2019, 11, 10540.
(b) Zou, J.; Xue, L.; Yang, N.; Ren, Y.; Fan, Z.; Wang, W.; Si, W.; Zhang, Y.; Huang, W.; Dong, X. Mater. Chem. Front. 2019, 3, 2143.
[78] (a) Lu, X.; Chen, J.; Li, J.; Xia, B.; Xu, J.; Wang, Q.; Xie, C.; Fan, Q.; Huang, W. Biomater. Sci. 2019, 7, 3609.
(b) Zhu, J.; Zou, J.; Zhang, Z.; Zhang, J.; Sun, Y.; Dong, X.; Zhang, Q. Mater. Chem. Front. 2019, 3, 1523.
(c) Liu, B.; Wang, W.; Fan, J.; Long, Y.; Xiao, F.; Daniyal, M.; Tong, C.; Xie, Q.; Jian, Y.; Li, B.; Ma, X.; Wang, W. Biomaterials 2019, 217, 119301.
[79] (a) Sun, T.; Chen, X.; Wang, X.; Liu, S.; Liu, J.; Xie, Z. Mater. Chem. Front. 2019, 3, 127.
(b) Ou, C.; Zhang, Y.; Pan, D.; Ding, K.; Zhang, S.; Xu, W.; Wang, W.; Si, W.; Yang, Z.; Dong, X. Mater. Chem. Front. 2019, 3, 1786.
(c) Fan, Y.-T.; Zhou, T.-J.; Cui, P.-F.; He, Y.-J.; Chang, X.; Xing, L.; Jiang, H.-L. Adv. Funct. Mater. 2019, 29, 1806708.
[80] Zeng, X.; Xiao, Y.; Lin, J.; Li, S.; Zhou, H.; Nong, J.; Xu, G.; Wang, H.; Xu, F.; Wu, J.; Deng, Z.; Hong, X. Adv. Healthc. Mater. 2018, 7, 1800589.
[81] Alifu, N.; Zebibula, A.; Qi, J.; Zhang, H.; Sun, C.; Yu, X.; Xue, D.; Lam, J. W. Y.; Li, G.; Qian, J.; Tang, B. Z. ACS Nano 2018, 12, 11282.
[82] Li, T.; Li, C.; Ruan, Z.; Xu, P.; Yang, X.; Yuan, P.; Wang, Q.; Yan, L. ACS Nano 2019, 13, 3691.
[83] Gao, S.; Wei, G.; Zhang, S.; Zheng, B.; Xu, J.; Chen, G.; Li, M.; Song, S.; Fu, W.; Xiao, Z.; Lu, W. Nat. Commun. 2019, 10, 2206.
[84] Yao, D.; Wang, Y.; Zou, R.; Bian, K.; Liu, P.; Shen, S.; Yang, W.; Zhang, B.; Wang, D. ACS Appl. Mater. Interfaces 2020, 12, 4276.
[85] (a) Zhu, H.; Cheng, P.; Chen, P.; Pu, K. Biomater. Sci. 2018, 6, 746.
(b) Xu, J.; Xia, B.; Niu, X.; Cai, J.; Han, Z.; Wang, Q.; Lu, X.; Fan, Q.; Huang, W. Dyes Pigments 2019, 170, 107664.
[86] Wang, Q.; Dai, Y.; Xu, J.; Cai, J.; Niu, X.; Zhang, L.; Chen, R.; Shen, Q.; Huang, W.; Fan, Q. Adv. Funct. Mater. 2019, 29, 1901480.
[87] Wang, Q.; Xu, J.; Geng, R.; Cai, J.; Li, J.; Xie, C.; Tang, W.; Shen, Q.; Huang, W.; Fan, Q. Biomaterials 2020, 231, 119671.

近红外二区有机小分子荧光探针

Near-Infrared-II Fluorescence Probes Based on Organic Small Molecules

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 5

Recommended Articles

Metrics

Comments

[1]	Chen Yeqin, Chen Jinping, Yu Tianjun, Zeng Yi, Li Yi. Polysaccharide Matrix-Induced Room-Temperature Phosphorescence of Organic Small Molecules [J]. Acta Chimica Sinica, 2023, 81(5): 450-455.
[2]	Yanqin Huang, Lijun Li, Shupei Yang, Rui Zhang, Xingfen Liu, Quli Fan, Wei Huang. HA-AuNPs/FDF for Highly Sensitive Detection of Hyaluronidase, Tumor-targeting Fluorescence Cell Imaging and Phototherapy [J]. Acta Chimica Sinica, 2023, 81(12): 1687-1694.
[3]	Yanrong Jia, Guanlei Gao, Min Xia. Methods for Adjusting Mechanoluminescence Behaviors on Crystals of Purely Organic Small Molecules [J]. Acta Chimica Sinica, 2022, 80(9): 1309-1321.
[4]	Qi Wang, Hui Xia, Yanwei Xiong, Xinmin Zhang, Jie Cai, Chong Chen, Yicong Gao, Feng Lu, Quli Fan. Simple Preparation of Near-infrared-II Organic Small Molecule-based Phototheranostics by Manipulation of the Electron-donating Unit [J]. Acta Chimica Sinica, 2022, 80(11): 1485-1493.
[5]	Liu Ye, Yuan Jun, Zou Yingping, Li Yongfang. Research Progress of the FuranContaining Fused Ring Conjugated Organic Molecules and Polymers [J]. Acta Chim. Sinica, 2017, 75(3): 257-270.