Acta Chimica Sinica ›› 2001, Vol. 59 ›› Issue (10): 1763-1768. Previous Articles     Next Articles

Original Articles

烯酮缩胺与芳基异硫氰酸酯的反应: 合成异噻唑化合物 的一个途径

赵梅欣;王梅祥;黄志镗   

  1. 中国科学院化学研究所分子科学中心
  • 发布日期:2001-10-15

Reaction of ketene aminals with aryl isothiocyanates: A simple route to isothiazole compounds

Zhao Meixin;Wang Meixiang;Huang Zhitang   

  • Published:2001-10-15

Cyclic and acyclic ketene aminals with different electron withdrawing groups reacted with aryl isothiocyanates to give he corresponding α-carbon adducts in high yield which underwent oxidative cyclization with bromine to afford isothiazole compounds in moderate yield.

Key words: KETENE, ISOTHIOCYANATE, OXAZOLE, OXIDATION, RING CLOSURE REACTION

CLC Number: