卤代芳烃的无溶剂微波法高效合成有机锡化合物及原位自身偶联反应

doi:10.6023/cjoc201408026

摘要/Abstract

采用无溶剂微波加热合成方法, 通过Pd(PPh₃)₄催化卤代芳烃与Sn₂Bu₆的反应, 成功地合成了一系列有机锡化合物. 这一新方法不仅操作简单、反应快和效率高, 而且副产物少、污染小. 同时, 此方法还可顺利实现卤代芳烃的原位自身偶联反应.

关键词: 微波加热, 无溶剂, 有机锡化合物, 自身偶联, 原位

A novel approach for the synthesis of a variety of aryl stannanes from aryl halides and Sn₂Bu₆ by using Pd(PPh₃)₄ as catalyst is developed under microwave-irradiated and solvent-free conditions. This method offers the advantages of not only being simple, rapid and highly efficient, but also producing little byproduct and reducing pollution resulting from the use of solvent. Also, the procedure is applicable to the in-situ homo-coupling of aryl halides.

Key words: microwave heating, solvent-free, stannanes, homo-coupling, in-situ

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潘春娇, 刘敏, 段新红. 卤代芳烃的无溶剂微波法高效合成有机锡化合物及原位自身偶联反应[J]. 有机化学, 2015, 35(2): 472-477.

Pan Chunjiao, Liu Min, Duan Xinhong. Highly Efficient Synthesis of Stannanes from Aryl halides and Their in-situ Homo-Coupling under Microwave-Irradiated and Solvent-Free Conditions[J]. Chin. J. Org. Chem., 2015, 35(2): 472-477.

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