有机化学 ›› 2017, Vol. 37 ›› Issue (10): 2772-2775.DOI: 10.6023/cjoc201703007 上一篇    下一篇

研究简报

荞麦地鼠尾草根中的二萜类成分

夏光惠a, 李元平b, 毕德文b, 张兰军b, 李宏哲a, 高林花b, 王利勤b   

  1. a 云南中医学院中药学院 昆明 650500;
    b 云南师范大学化学化工学院 昆明 650500
  • 收稿日期:2017-03-02 修回日期:2017-05-22 发布日期:2017-06-02
  • 通讯作者: 王利勤 E-mail:kibwang@sohu.com
  • 基金资助:

    国家自然科学基金(No.31100143)资助项目.

Diterpenes from the Roots of Salvia kiaometiensis Lévl

Xia Guanghuia, Li Yuanpingb, Bi Dewenb, Zhang Lanjunb, Li Hongzhea, Gao Linhuab, Wang Liqinb   

  1. a College of Pharmaceutical Science, Yunnan University of Traditional Chinese Medicine, Kunming 650050;
    b Faculty of Chemistry and Engineering, Yunnan Normal University, Kunming 650050
  • Received:2017-03-02 Revised:2017-05-22 Published:2017-06-02
  • Contact: 10.6023/cjoc201703007 E-mail:kibwang@sohu.com
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No.31100143).

对民间丹参代用品荞麦地丹参(Salvia kiaometiensis Lévl.)乙醇提取物进行化学成分研究,通过现代多种色谱技术和波谱技术,从中分离并鉴定16个二萜类化合物,分别是6,8,11,13-abietatetraen-12-ol dimer(1),kiaometin(2),miltirone(3),tanshinone ⅡA(4),crypotanshione(5),tanshindiol C(6),ferruginol(7),2-isopropyl-8-methylphenanthrene-3,4-dione(8),tanshinone I(9),trijuganone B(10),dihydrotanshinone I(11),grandifolias C(12),przewalskin(13),tanshinlactone(14),6,7,8,9-tetrahydro-1,6,6-trimethylfuro[3,2-c]naphtha[2,1-e]oxepine-10,12-dione(15),almilalbanone(16).其中,化合物1为新的松香烷型二萜的二聚体,2为新的降松香烷型二萜化合物,其B环7,8位开环后又通过醚桥连接起来.所有化合物均为首次从该种植物中得到.

关键词: 荞麦地鼠尾草, 鼠尾草属, 唇形科, 松香烷型二萜

Through a variety of chromatographic techniques and spectroscopic methods, sixteen diterpenes were isolated and identified from the ethanol extraction of the roots of Salvia kiaometiensis Lévl. Their structures were identified to be 6,8,11,13-abietatetraen-12-ol dimer (1), kiaometin (2), miltirone (3), tanshinone ⅡA (4), crypotanshione (5), tanshindiol C (6), ferruginol (7), 2-isopropyl-8-methylphenanthrene-3,4-dione (8), tanshinone I (9), trijuganone B (10), dihydrotanshinone I (11), grandifolias C (12), przewalskin (13), tanshinlactone (14), 6,7,8,9-tetrahydro-1,6,6-trimethylfuro[3,2-c]naphtha[2,1-e]oxepine-10,12-dione (15), and salmilalbanone (16). Compound 1 is a new abietane diterpenes dimer, and compound 2 is a new 7,8:7,20-diepoxy-nor-abietane diterpenes. All of the diterpenes were isolated from this plant for the first time.

Key words: Salvia kiaometiensis, Salvia, Lamiaceae, abietane diterpenes