咪唑并[1,2-a]吡啶C-3位C—H官能团化研究进展

doi:10.6023/cjoc201709044

有机化学 ›› 2018, Vol. 38 ›› Issue (4): 775-790.DOI: 10.6023/cjoc201709044 上一篇下一篇

所属专题：碳氢活化合辑2018-2019

综述与进展

咪唑并[1,2-a]吡啶C-3位C—H官能团化研究进展

金城安^a, 徐庆^a, 冯高峰^a, 金阳^a,b, 张连阳^b,c

a 绍兴文理学院化学化工学院绍兴 312000;
b 绍兴文理学院浙江省清洁染整技术研究重点实验室绍兴 312000;
c 绍兴文理学院纺织服装学院绍兴 312000

收稿日期:2017-09-26 修回日期:2017-11-08 发布日期:2017-11-17
通讯作者: 张连阳 E-mail:zhlysheep@163.com
基金资助:
绍兴文理学院校级科研（No.2016LG1011）资助项目.

Progress in C—H Bond Functionalization on C-3 Position of Imidazo[1,2-a] pyridines

Jin Cheng'an^a, Xu Qing^a, Feng Gaofeng^a, Jin Yang^a,b, Zhang Lianyang^b,c

a College of Chemistry and Chemical Engineering, Shaoxing University, Shaoxing 312000;
b Key Laboratory of Clean Dyeing and Finishing Technology of Zhejiang Province, Shaoxing University, Shaoxing 312000;
c College of Textile and Garment, Shaoxing University, Shaoxing 312000

Received:2017-09-26 Revised:2017-11-08 Published:2017-11-17
Contact: 10.6023/cjoc201709044 E-mail:zhlysheep@163.com
Supported by:
Project supported by the Research Project of Shaoxing University (No. 2016LG1011).

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摘要/Abstract

3-取代咪唑并[1，2-a]吡啶类化合物是一类重要的含氮稠环化合物，在医药、材料等领域具有广泛的应用价值.C-3位C-H官能团化是构建3-取代咪唑并[1，2-a]吡啶类化合物的简单有效方法.按咪唑并[1，2-a]吡啶C-3位的成键类型（C-C、C-S/Se、C-N/P）进行分类，主要介绍了近几年来咪唑并[1，2-a]吡啶等氮杂稠环化合物C-3位C-H官能团化反应进展，并对今后发展作出了展望.

关键词: 3-取代咪唑并[1,2-a]吡啶, C-H官能团化, C-3位

3-Substituted imidazo[1,2-a] pyridines are important N-fused heterocycles with extensive application value in medicine, materials and other fields. C(3)-H bond functionalization strategy was a simple and effective way to build 3-substituted imidazo[1,2-a] pyridines. The recent advances of the access to 3-substituted imidazo[1,2-a] pyridines according to the type of bonding (C-C, C-S/Se, C-N/P) on C-3 position are briefly summarized, and a prospect for the future development is made.

Key words: 3-substituted imidazo[1,2-a] pyridine, C-H bond functionalization, C-3 position

引用此文

金城安, 徐庆, 冯高峰, 金阳, 张连阳. 咪唑并[1,2-a]吡啶C-3位C—H官能团化研究进展[J]. 有机化学, 2018, 38(4): 775-790.

Jin Cheng'an, Xu Qing, Feng Gaofeng, Jin Yang, Zhang Lianyang. Progress in C—H Bond Functionalization on C-3 Position of Imidazo[1,2-a] pyridines[J]. Chin. J. Org. Chem., 2018, 38(4): 775-790.

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咪唑并[1,2-a]吡啶C-3位C—H官能团化研究进展

Progress in C—H Bond Functionalization on C-3 Position of Imidazo[1,2-a] pyridines

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