有机化学 ›› 1991, Vol. 11 ›› Issue (3): 294-298. 上一篇    下一篇

研究论文

1-(5-苄基四唑-2-乙酰基)-4-芳酰胺基硫脲及其环化产物的合成

冯小明;陈荣;张进忠   

  1. 西南师范大学化学系
  • 发布日期:1991-06-25

Synthesis of 1-(5-benzyltetrazol-2-acetyl)-4-aroylthiosemicarbazides and their cyclized production

FENG XIAOMING;CHEN RONG;ZHANG JINZHONG   

  • Published:1991-06-25

本文合成了一系列新的1-(5-苄基四唑-2-乙酰基)-4-芳酰胺基硫脲(2)。2在8%NaOH溶液作用下, 环化为3-(5-苄基四唑-2-亚甲基)-4-芳酰基-1,2,4-三唑啉-5-硫酮(3)。

关键词: 苯甲酰胺 P, 质子磁共振谱法, 四唑 P, 硫酮, 红外分光光度法, 质谱法, 元素分析, 硫脲类, 甲苯 P, 三唑 P

Refluxing (5-benzyltetrazol-2-yl)acetylhydrazine with RC(O)NCS (R = Ph, substituted Ph, PhCH:CH, a-naphthylmethyl) in MeCN for 4 h gave 43.8-79.1% the title compounds I which were refluxed with aqueous 8% NaOH to give 41.8-82.0% triazolines II.

Key words: THIOKETONE, BENZAMIDE P, INFRARED SPECTROPHOTOMETRY, PROTON MAGNETIC RESONANCE SPECTROMETRY, TETRAZOLE P, MASS SPECTROGRAPHY, METHYLBENZENE P, ELEMENTAL ANALYSIS, SULFOCARBAMIDES, PYRRODIAZOLE P

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