有机化学 ›› 1991, Vol. 11 ›› Issue (3): 314-317. 上一篇    下一篇

研究论文

异色满并三氮杂 酮化合物的合成

王进军;欧阳杰;李华;姜贵吉   

  1. 吉林化工学院精细化工系;延边大学化学系;化学工业部第一胶片厂研究所
  • 发布日期:1991-06-25

Synthesis of inochromanotriazepine compounds

WANG JINJUN;OU YANGJIE;LI HUA;JIANG GUIJI   

  • Published:1991-06-25

本文选择[1,2,4]三氮杂 酮类的七员环系与异色满并环, 旨在寻找抗癌新药。

关键词: 苯并咪唑 P, 氮杂环化合物, 质子磁共振谱法, 苯并咪唑 P, 抗癌药, 元素分析, 红外分光光度法, 萘 P, 氧杂环化合物, 萘 P

Condensation of b-keto ester of isochroman with benzothiazol-2-ylhydrazine (I), semicarbazide and its analogs and 1,2-diamino-1H-benzimidazole has been used to synthesized several isochromanotriazepines. E.g., refluxing ester II with I in HOAc gave 68% isochromanotriazepine III.

Key words: BENZIMIDAZOLE P, BENZIMIDAZOLE P, ANTICARCINOGEN, NITROGEN HETEROCYCLICS, PROTON MAGNETIC RESONANCE SPECTROMETRY, ELEMENTAL ANALYSIS, OXYGEN HETEROCYCLICS, INFRARED SPECTROPHOTOMETRY, NAPHTHALENE P, NAPHTHALENE P

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