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有机化学
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有机化学 ›› 1995, Vol. 15 ›› Issue (5): 449-460.    下一篇

研究论文

含氨基酸Schiff碱-金属手性配合物的合成及其相关反应进展

王积涛;许育明;杨晓萍;袁耀锋   

  1. 南开大学化学系
  • 发布日期:1995-10-25

Survey of chiral metal complexes with Schiffbase derived from amino acids and their related reactions

WANG JITAO;XU YUMING;YANG XIAOPING;YUAN YAOFENG   

  • Published:1995-10-25

被引次数

65

本文综述了"含氨基酸Schiff碱-金属"手性配合物的合成及其结构。同时还讨论了"含氨基酸Schiff碱-金属"手性配合物不对称反应, 如: 烷基化反应、缩合反应、Michael加成反应、溴化反应等。这些反应为氨基酸拆分及非蛋白质类氨基酸合成提供了新方法。

关键词: 手征性, 氨基酸, 缩合反应, 席夫碱, 迈克尔加成反应, 烷基化, 金属络合物

Synthesis of chiral metal complexes with Schiffbase derived from amino acids and their structures were summarized. Meanwhile asymmetric reactions of the chiral complexes were discussed, such as, alkylation, condensation with aldehydes, Micheal addition to activated olefins. These reactions provide a new method for resolving recemic amino acids and synthesizing non-protein amino acids.

Key words: AMINO ACID, CONDENSATION REACTION, CHIRALITY, SCHIFF BASE, ALKYLATION, MICHAEL ADDITION REACTION, METAL COMPLEX

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