有机化学 ›› 2000, Vol. 20 ›› Issue (2): 224-227. 上一篇    下一篇

研究论文

组合化学法筛选聚苯乙烯固载季铵盐相转移催化剂研究(I)

徐满才;欧植泽;俞善信   

  1. 湖南师范大学化学系.长沙(410006)
  • 发布日期:2000-04-25

Screening polystyrene - supported quaternary ammonium salt as phasetransfer catalysts using a combinatorial chemical method

Xu Mancai;Ou Zhize;Yu Shanxin   

  1. Hunan Normal Univ, Dept Chem.Changsha(410006)
  • Published:2000-04-25

利用组合化学方法合成了一个含有60种不同结构的聚苯乙烯固载季铵盐相转移催化剂的催化剂库,以有外加碱条件下亲核取代反应为探针反应,利用迭代法从中筛选出了活性最高的催化剂,建立了一种快速合成和筛选聚苯乙烯固载季铵盐相转移催化剂的方法。

关键词: 聚苯乙烯, 季铵, 相转移催化剂, 数据库, 组合化学, 亲核反应, 取代反应, 筛选

A phase transfer catalyst (PTC) library of sixty different polystyrene - supported quaternary ammonium salt catalysts was synthesized. The nycleophilic Substitution reaction under basic conditions was used as a probe reaction to identify the most active PTC in the library by using the iterative method, and a method ofrapid synthesis and screening polystyrene - supported quaternary ammonium PTC was established.

Key words: POLYSTYRENE, QUATERNARY AMMONIUM COMPOUNDS, PHASE TRANSFER CATALYST, DATE BASE, NUCLEOPHILIC REACTION, SUBSTITUTION REACTION, SELECTION

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