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有机化学
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有机化学 ›› 2002, Vol. 22 ›› Issue (11): 917-921. 上一篇    下一篇

研究论文

三个新甾体皂甙元的结构鉴定

黄金文;蒋山好;谭昌恒;朱大元   

  1. 中国科学院上海生命科学研究院.上海(200031)
  • 发布日期:2002-11-25

Structural elucidation of three new steroid sapogenins

Huang Jinwen;Jiang Shanhao;Tan Changheng;Zhu Dayuan   

  1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences.Shanghai(200031)
  • Published:2002-11-25

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被引次数

35 | 3

从中药蒺藜Tribulus terrestrisL.(Zygophyllaceae）中分离纯化得到5个 甾体皂甙元，经IR，2D-NMR和MS等波谱技术分别鉴定为：海可皂甙元(1)，25(R)-螺 甾烷-4—烯—3，12—酮(2)，25(R)·螺甾烷—3，5-二烯—12—酮(3)，25(R)-螺 甾烷-4—烯—2β，3α-二羟基—12—酮(4)和25(R)—螺甾烷—24β—羟基-4—烯 —3，12—酮(5)，其中化合物3-5为新化合物．

关键词: 蒺藜;甾体皂甙元;螺甾烷类;中药;红外光谱学;质谱;核磁共振;结构, 鉴定

Three new steroid sapogenins, 24(R)-spirostane-3,5-diene-12-one (3), 24(R)-spirostane-2β, 3α-diol-4-ene-12-one (4), 24(R)-spirostane-24β- ol-4-ene-3,12-dione (5), together with two known compounds, hecogenin (1), and 24(R)-spirostane-4-ene-3,12-dioen (2), were isolated from Tribulus terrestris L. Their structures were elucidated by the spectral analyses.

Key words: Tribulus terrestris L. ;steroid sapogenin;SPIROSTANES, CHINESE DRUG;INFRARED SPECTROSCOPY;MASS SPECTRA, NUCLEAR MAGNETIC RESONANCE;STRUCTURE;IDENTIFICATION

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