有机化学 ›› 2003, Vol. 23 ›› Issue (3): 221-229. 上一篇    下一篇

研究论文

非水介质中酶催化的反应研究新进展

沈鸿雁;田桂玲;叶蕴华   

  1. 北京大学化学与分子工程学院
  • 发布日期:2003-03-25

Recent Progress in the Study on Enzymatic Reactions in Non-aqueous Media

Shen Hongyan;Tian Guiling;Ye YunHua   

  1. Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Minsistry of Education,College of Chemistry and Moleculor Engineering, Pelking University
  • Published:2003-03-25

介绍了非水介质中酶催化反应有机合成中的应用及手性化合物的酶促拆分与合 成反应,分析了冷冻干燥保护剂和修饰剂对酶性质的影响,论述了固定化酶在有机 溶剂中的应用,并讨论了影响固定化酶性质的因素。

关键词: 酶促合成, 固定化酶, 应用, 影响因素

The new development of enzymatic reactions in non-aqueous media for organic synthesis is reviewed. The enzyme-catalyzed kinetic resolution and enantioselective synthesis in non-aqueous media, the influence of lyoprotectants and chemical modification on enzyme properties, the factors affecting the activity and stability of immobilized enzymes are introduced and discussed.

Key words: ENZYMATIC SYNTHESIS, FIXED ENZYME, APPLICATION, INFLUENCING FACTORS

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