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有机化学
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有机化学 ›› 2005, Vol. 25 ›› Issue (12): 1542-1547. 上一篇    下一篇

综述与进展

硫化物的生物氧化成手性亚砜

姜标，黄浩，罗军，李祖义*   

  1. (中国科学院上海有机化学研究所 上海 200032)
  • 收稿日期:2005-06-01 修回日期:2005-09-30 发布日期:2005-11-30
  • 通讯作者: 李祖义

Chiral Sulfoxides by Biooxidation of Sulfides

JIANG Biao, LUO Jun, HUANG Hao, LI Zu-Yi*   

  1. (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032)
  • Received:2005-06-01 Revised:2005-09-30 Published:2005-11-30
  • Contact: LI Zu-Yi

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865

被引次数

21

描述了硫化物不对称生物氧化成手性亚砜, 主要为氯过氧化物酶、环己酮单氧酶催化有机硫化物氧化成具有光学活性的亚砜的两条酶促反应途径.

关键词: 硫氧化物, 氯过氧化物酶, 环己酮单氧酶

This review was mainly focused on the catalytic asymmetric biooxidation of sulfides to chiral sulfoxides. Two enzymatic approaches in the oxidation of organic sulfides to optically active sulfoxides are described based on the use of chloroperoxidase and cyclohexanone monooxygenase.

Key words: chloroperoxidase, sulfoxides, cyclohexanone monooxygenase