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有机化学
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有机化学 ›› 2008, Vol. 28 ›› Issue (08): 1483-1486. 上一篇    下一篇

研究简报

3-芳基-6-对氯苯甲酰氨基均三唑并[3,4-b]-1,3,4-噻二唑的 合成及生物活性

覃章兰* ; 张 欣

  

  1. (华中师范大学化学学院 武汉 430079)
  • 收稿日期:2008-01-17 修回日期:2008-04-10 发布日期:2008-08-18
  • 通讯作者: 覃章兰

Synthesis and Fungicidal Activity of 3-Aryl-6-(p-chlorobenzoylamino)- s-triazolo(3,4-b)-1,3,4-thiadiazoles

QING, Zhang-Lan*; ZHANG, Xin

  

  1. (Department of Chemistry, Central China Normal University, Wuhan 430079)
  • Received:2008-01-17 Revised:2008-04-10 Published:2008-08-18
  • Contact: QING, Zhang-Lan

PDF

680

被引次数

45

利用3-芳基-4-氨基-5-巯基-1,2,4-均三唑和对氯苯甲酰异硫氰酸酯在乙腈中反应, 得到一系列3-芳基-6-对氯苯甲酰氨基均三唑并[3,4-b]-1,3,4-噻二唑, 用1H NMR, IR, MS和元素分析确定了其结构, 并对其进行了抑菌活性测试.

关键词: 均三唑并[3,4-b]-1,3,4-噻二唑, 合成, 抑菌活性

The reaction of 3-aryl-4-amino-5-mercapto-1,2,4-s-triazale with p-chlorobenzoyl isothiocyanate in the presence of absolute acetonitrile yielded a series of 3-aryl-6-(p-chlorobenzoylamino)-s-triazolo(3,4-b)- 1,3,4-thiadiazoles, with the structures determined by 1H NMR, IR, mass spectra and elemental analysis, and the fungicidal activities tested.

Key words: s-triazolo(3,4-b)-1,3,4-thiadiazole, fungicidal activity, synthesis