有机化学 ›› 2010, Vol. 30 ›› Issue (07): 958-967. 上一篇    下一篇

综述与进展

米氏酸在杂环化合物合成中的应用研究进展

高文涛*,郑美茹,侯文端   

  1. (渤海大学超精细化学品研究所 辽宁省应用化学重点实验室 锦州 121000)
  • 收稿日期:2009-07-20 修回日期:2009-09-22 发布日期:2009-12-08
  • 通讯作者: 高文涛 E-mail:bhuzh@163.com
  • 基金资助:

    辽宁省高校重点实验室(No. 2008s001)资助项目

Progress in Application of Meldrum s Acid to Synthesis of Heterocyclic Compounds

GAO Wen-Tao, ZHENG Mei-Ru, HOU Wen-Duan   

  1. (Liaoning Key Laboratory of Applied Chemistry, Institute of Superfine Chemicals, Bohai University, Jinzhou 121000)
  • Received:2009-07-20 Revised:2009-09-22 Published:2009-12-08
  • Contact: Wentao Gao E-mail:bhuzh@163.com

综述了近年来米氏酸在杂环化合物合成中的应用, 涉及到吡喃环、吡啶环、呋喃环、吡咯环、噁唑环和异噁唑环重要杂环的形成. 大多具有反应条件温和、便利、产率较高等优点.

关键词: 米氏酸, 杂环化合物, 合成, 应用

The applications of Meldrum s acid to synthesis of heterocyclic compounds in recent years are reviewed. All the heterocyclic compounds are related to pyranoid, pyridine, furan, pyrrole, oxazole and isoxazole rings. Most mentioned synthetic methods have the advantages of mild reaction conditions, easy operation and high yields.

Key words: Meldrum s acid, heterocyclic compound, synthesis, application

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