关键词: 类卡宾, 环烷基化, 手性合成, 环丙烷氨基酸

This paper reviews the recent progress in the synthesis of cyclopropane amino acids. General approaches involve the nucleophilic cycloalkylation, carbenoids addition of certain amino acid derivatives and derivatization from simple cyclopropane compounds. Chiral synthesis can be achieved by taking advantage of natural or synthetic optically active compounds.

Key words: CYCLOALKYLATION, CARBENOID