有机化学 ›› 1996, Vol. 16 ›› Issue (4): 289-300.    下一篇

研究论文

抗体酶催化化学反应的新进展

黄启斌   

  1. 中国人民解放军防化研究院
  • 发布日期:1996-08-25

Recent development in abzyme-catalyzed chemical transformations

HUANG QIBIN   

  • Published:1996-08-25

本文评述了近几年来抗体酶催化化学反应的研究进展, 包括酯和酰胺的水解反应、脱羧反应、Claisen重排、Diels-Alder反应、不对称诱导作用、β-消去反应、金属络合物作用、氧化-还原反应、光诱导聚合和消除反应等, 讨论了介质效应和反应机理。

关键词: 催化反应, 抗体酶

This paper reviews the developments in the chemical transformations catalyzed by abzymes, including ester and amide hydrolysis, decarboxylation, Claisen rearrangement, Diels-Alder reaction, asymmetric induction, β-elimination, metal chelation, redox, photo-induced dimerization and cleavage, etc. Medium effects and reaction mechanisms were discussed.

Key words: ABZYME, CATALYTIC REACTION

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