有机化学 ›› 2000, Vol. 20 ›› Issue (5): 735-737. 上一篇    下一篇

研究论文

1,5-苯并硫氮杂卓α-氨基-β-内酰胺的合成和立体 结构研究

孙娜;张萍;李媛;金声   

  1. 河北师范大学化学系.石家庄(050016);北京大学化学与分子工程学院
  • 发布日期:2000-10-25

\the synthesis and sterochemistry of 1,5-benzothiazepines-α-amino-β -lactam derivatives

Sun Na;Zhang Ping;Li Yuan;Jin Sheng   

  1. Hebei Teachers Univ, Dept Chem.Shijiazhuang(050016)
  • Published:2000-10-25

合成了6个1,5-苯并硫氮杂卓α-氨基-β-内酰胺化合物,用MS、^1HNMR和元素分析对其结构进行了确证,并用X-射线衍射法确定了此类化合物的立体结构。

关键词: 苯并硫氮杂卓P, β内酰胺, 苯并硫氮杂P, 苯并二氮杂卓, X射线衍射分析, 立体结构

Six β-lactam derivatives of 1,5-benzothiazepines were synthesized by reaction of 1,5-benzothiazepines with N-protected glycine. The structure, configuration and conformation of the products were determinted by MS, ^1H NMR, elementary analysis and X-ray diffraction.

Key words: BETA LACTAM, BENZOTHIAZEPINE P, DIAZEPAM, X-RAY DIFFRACTION ANALYSIS, SPATIAL STRUCTURE

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