有机化学 ›› 2000, Vol. 20 ›› Issue (5): 731-734. 上一篇    下一篇

研究论文

N'-4,5,6-三取代嘧啶-2-基-N-邻磺酰苯甲酰亚胺基乙 酰脲的合成(Ⅰ)

薛思佳;王涛;廖展如   

  1. 华中师范大学化学系.武汉(430070)
  • 发布日期:2000-10-25

Synthesis of N'-4,5,6trisubstituted-2-pyrimidin-yl-N-2- sulfonylbenzoyl-imino acetylureas

Xue Sijia;Wang Tao;Liao Zhanru   

  1. Huazhong Normal Univ, Dept Chem.Wuhan(430070)
  • Published:2000-10-25

根据药物化学中的生物电子等排原理,采用“亚结构连接法”设计合成了11种未见文献报道的标题化合物,它们的结构经IR、^1HNMR、MS和元素分析测试而确定,初步生物活性测定结果表明,部分标题化合物具有良好的植物生长调节活性。

关键词: 嘧啶P, 取代脲类除草剂, 环亚胺, 苯磺酰胺P, 苯磺酰亚胺P, 植物生长调节剂, 生物活性, 波谱分析

Eleven new compounds were designed and synthesined using "Substrmture Link Wory" according to the bioisosterism principles. Their structures were confirmed by IR、^1H NMR、 MS and elemental analysis. The preliminary results of biological activity test showed that some of them had good biological activities against root of rape.

Key words: PYRIMIDINE P, PHENYL UREA GROUP HERBICIDES, TRIHEXYPHENIDYL, BENZENESULFONAMIDE P, PLANT GROWTH REGULATORS, BIOLOGICAL ACTIVITY, SPECTROMETRIC ANALYSIS

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