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有机化学
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有机化学 ›› 2017, Vol. 37 ›› Issue (6): 1577-1581.DOI: 10.6023/cjoc201701016 上一篇    下一篇

研究简报

阿拉华蜡孔菌中四个新的2，5-二取代呋喃邻二醇(英文)

刘良燕a, 冯涛b, 李正辉b, 刘吉开b   

  1. a. 云南农业大学农学与生物技术学院 昆明 650201;
    b. 中南民族大学药学院 武汉 430074
  • 收稿日期:2017-01-07 修回日期:2017-01-20 发布日期:2017-01-20
  • 通讯作者: 刘吉开 E-mail:jkliu@mail.kib.ac.cn
  • 基金资助:

    Project supported by the National Natural Science Foundation of China (Nos. 21502167, 81561148013).

Four New 2,5-Disubstituted Furan Vicinal Diols from the Fungus Ceriporia alachuana

Liu Liangyana, Feng Taob, Li Zhenghuib, Liu Jikaib   

  1. a. College of Agronomy and Biotechnology, Yunnan Agricultural University, Kunming 650201;
    b. School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074
  • Received:2017-01-07 Revised:2017-01-20 Published:2017-01-20
  • Contact: 10.6023/cjoc201701016 E-mail:jkliu@mail.kib.ac.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21502167, 81561148013).

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补充材料

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从阿拉华蜡孔菌发酵液中分离鉴定四个呋喃邻二醇，1R，2R-1-[5-（戊-4-烯-1-基）呋喃-2-基]丙烷-1，2-二醇（1），1S，2R-1-[5-（戊-4-烯-1-基）呋喃-2-基]丙烷-1，2-二醇（2）、1R，2R-1-[（5-戊基）呋喃-2-基]丙烷-1，2-二醇（3）和1R，2S-1-[（5-戊基）呋喃-2-基]丙烷-1，2-二醇（4）.综合运用波谱分析（1D、2D NMR，HRMS）、化学法（异丙叉衍生物）和乙酸钼二聚体[Mo2（OAc）4]诱导CD谱等方法确定了化合物1~4的绝对构型.

关键词: 邻二醇, 阿拉华蜡孔菌, 诱导CD谱, 乙酸钼二聚体

Four new closely related vicinal diols, (1R,2R)-1-(5-(pent-4-en-1-yl)furan-2-yl)propane-1,2-diol (1), (1S,2R)-1-(5-(pent-4-en-1-yl)furan-2-yl)propane-1,2-diol (2), (1R,2R)-1-(5-pentylfuran-2-yl)propane-1,2-diol (3) and (1R,2S)-1-(5-pen-tylfuran-2-yl)propane-1,2-diol (4), were isolated from the cultures of the fungus Ceriporia alachuana. Their structures and absolute configurations were totally determined by spectroscopic means, chemical method (forming di-O-isopropylidene derivative) and Mo2(OAc)4 induced circular dichroism (ICD) experiments.

Key words: vicinal diols, Ceriporia alachuana, induced circular dichroism (ICD), dimolybdenum tetraacetate