有机化学 ›› 2018, Vol. 38 ›› Issue (6): 1562-1565.DOI: 10.6023/cjoc201712006 上一篇    下一篇

研究简报

姜黄中两个新没药烷型倍半萜成分的研究

黄超, 唐宇, 黄婷, 王立军, 江维, 麻光磊, 熊娟, 胡金锋   

  1. 复旦大学药学院 天然药物化学教研室 上海 201203
  • 收稿日期:2017-12-04 修回日期:2018-01-10 发布日期:2018-02-06
  • 通讯作者: 胡金锋,E-mail:jfhu@fudan.edu.cn E-mail:jfhu@fudan.edu.cn
  • 基金资助:

    国家自然科学基金(Nos.81773599,21472021)和科技部基金(No.2018ZX09735008)资助项目.

Two New Bisabolane-Type Sesquiterpenoids from Curcuma longa

Huang Chao, Tang Yu, Huang Ting, Wang Lijun, Jiang Wei, Ma Guanglei, Xiong Juan, Hu Jinfeng   

  1. Department of Natural Products Chemistry, School of Pharmacy, Fudan University, Shanghai 201203
  • Received:2017-12-04 Revised:2018-01-10 Published:2018-02-06
  • Contact: 10.6023/cjoc201712006 E-mail:jfhu@fudan.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 81773599, 21472021) and the Ministry of Science and Technology (MOST) (No. 2018ZX09735008).

从购自安徽亳州中药材市场的姜黄(Curcuma longa L.)切片95%乙醇提取物中,除主要没药烷型倍半萜类成分芳姜黄酮[(+)-(S)-ar-turmerone]外,还分离得到2个新的同类化合物,turmerones E(1)和F(2).它们的结构通过质谱、一维/二维核磁共振谱和圆二色谱(ECD)等波谱和光谱技术得以确定.

关键词: 姜黄, 没药烷型倍半萜, turmerone E, turmerone F

Two new[named turmerones E (1) and F (2), resp.] and one major known[i.e., (+)-(S)-ar-turmerone] bisabolane-type sesquiterpenoids were isolated from the 95% EtOH extract of the rhizome of Curcuma longa. The structures were determined by spectroscopic data (IR, UV, 1D/2D NMR, ECD, HRESIMS) and/or comparing with those reported physicochemical data in related literature.

Key words: Curcuma longa, bisabolane-type sesquiterpenoids, turmerone E, turmerone F