有机化学 ›› 2019, Vol. 39 ›› Issue (3): 848-851.DOI: 10.6023/cjoc201807059 上一篇    下一篇

研究简报

纤枝金丝桃中3个新多环多异戊烯基间苯三酚类成分

王扣a, 王赟a, 王子明a, 丁林芬a, 胡建林a, 陈佳b   

  1. a 昆明医科大学药学院暨云南省天然药物药理重点实验室 昆明 650500;
    b 云南中医药大学 云南省傣医药与彝医药重点实验室 昆明 650500
  • 收稿日期:2018-07-31 修回日期:2018-10-19 发布日期:2018-11-26
  • 通讯作者: 王扣, 陈佳 E-mail:koko_yaya@163.com;chenjia@ynutcm.edu.cn
  • 基金资助:

    国家自然科学基金(No.20402072)、昆明医科大学“百名中青年学术和技术骨干”培养计划(No.60117190410)和云南省重点实验室培育计划(No.2017DG006)资助项目.

Three New Polycyclic Polyprenylated Acylphloroglucinols from Hypericum lagarocladum

Wang Koua, Wang Yuna, Wang Ziminga, Ding Linfena, Hu Jianlina, Chen Jib   

  1. a School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650500;
    b Yunnan Key Laboratory of Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming 650500
  • Received:2018-07-31 Revised:2018-10-19 Published:2018-11-26
  • Contact: 10.6023/cjoc201807059 E-mail:koko_yaya@163.com;chenjia@ynutcm.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 20402072), the Program of One Hundred Young and Middle-aged Academic and Technical Talents of Kunming Medical University (No. 60117190410), and the Key Laboratory Training Program in Yunnan Province (No. 2017DG006).

利用多种色谱分离方法对纤枝金丝桃的化学成分进行研究,从其甲醇提取物的石油醚萃取部位分离得到3个新化合物,其结构经HRMS,1D和2D NMR等多种现代波谱鉴定为hyperlagarin A(1)、hyperlagarin B(2)和hyperlagarin C(3).

关键词: 纤枝金丝桃, 化学成分, 多环多异戊烯基间苯三酚

Three new polycyclic polyprenylated acylphloroglucinols (PPAPs) were isolated from Hypericum lagarocladum by means of various chromatographic techniques. Their structures were identified as hyperlagarin A (1), hyperlagarin B (2), and hyperlagarin C (3) on the basis of extensive spectroscopic analyses, including HRMS, 1D-and 2D-NMR.

Key words: Hypericum lagarocladum, chemical constituent, polycyclic polyprenylated acylphloroglucinols