有机化学 ›› 2019, Vol. 39 ›› Issue (6): 1704-1710.DOI: 10.6023/cjoc201903018 上一篇    下一篇

所属专题: 金属有机化学 元素有机化学合辑2018-2019 有机硅化学虚拟合辑

研究论文

钴催化芳香族烯烃的脱氢硅化反应

程彪, 陆鹏, 赵家金, 陆展   

  1. 浙江大学化学系 杭州 310058
  • 收稿日期:2019-03-10 修回日期:2019-04-03 发布日期:2019-04-16
  • 通讯作者: 陆展 E-mail:luzhan@zju.edu.cn
  • 基金资助:

    国家自然科学基金(No.21772171)、国家重点基础研究发展计划(No.2015CB856600)、浙江省自然科学基金(No.LR19B020001)、浙江大学曹光彪高科技发展基金和浙江大学基本科研业务费资助项目.

Cobalt-Catalyzed Dehydrogenative Silylation of Vinylarenes

Cheng Biao, Lu Peng, Zhao Jiajin, Lu Zhan   

  1. Department of Chemistry, Zhejiang University, Hangzhou 310058
  • Received:2019-03-10 Revised:2019-04-03 Published:2019-04-16
  • Contact: 10.6023/cjoc201903018 E-mail:luzhan@zju.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21772171), the National Basic Research Program of China (973 Program, No. 2015CB856600), the Zhejiang Provincial Natural Science Foundation (No. LR19B020001), the K. P. Chao's High Technology Development Foundation of Zhejiang University and the Fundamental Research Funds for the Central Universities.

描述了一种钴催化的高化学、区域、立体选择性的芳香族烯烃的脱氢硅化反应.亚胺吡啶咪唑啉的钴络合物可以有效促进该反应,并能显著提高该反应的化学选择性.该方法利用地球丰产过渡金属、廉价易得的烯烃和硅烷来构建具有高附加值的烯基硅烷.文中同时描述了该反应可放大到克级规模制备及可能的反应机理.

关键词: 钴催化, 脱氢硅化, 烯烃, 烯基硅, 区域和立体选择性

A highly chemo-, regio-, and stereo-selective cobalt-catalyzed dehydrogenative silylation of vinylarenes was described. The imidazoline iminopyridine cobalt complex could promote this reaction effectively and improve the chemoselectivity dramatically. This protocol used earth-abundant transition metal, readily available alkenes and hydrosilanes to construct valuable vinylsilanes. The reaction could be carried out in gramscale and the proposed mechanism was also described.

Key words: cobalt-catalyzed, dehydrogenative silylation, alkenes, vinylsilanes, regio-and stereo-selectivity