垂穗石松中一个新的千层塔三萜

doi:10.6023/cjoc202004006

有机化学 ›› 2020, Vol. 40 ›› Issue (8): 2531-2534.DOI: 10.6023/cjoc202004006 上一篇下一篇

研究简报

垂穗石松中一个新的千层塔三萜

金玉^a,c, 黄政皖^a,c, 黄英娜^b, 徐莺婷^a,c, 颜健^d, 杨洁^b, 周忠玉^a, 魏孝义^a

a 中国科学院华南植物园中国科学院植物资源保护与可持续利用重点实验室广东省应用植物学重点实验室广州 510650;
b 南方医科大学广东省新药筛选重点实验室广州市新发病毒防治药物研究重点实验室广州 510515;
c 中国科学院大学北京 100049;
d 华南农业大学资源环境学院农业农村部华南热带农业环境重点实验室广东省生态循环农业重点实验室广东省现代生态循环农业工程中心广州 510642

收稿日期:2020-04-03 修回日期:2020-04-27 发布日期:2020-06-01
通讯作者: 杨洁, 周忠玉 E-mail:yj528@smu.edu.cn;zhouzhongyu@scbg.ac.cn
基金资助:
国家自然科学基金（No.31970376）、中国科学院青年创新促进会会员（No.2016310）、广州市科技计划（No.201904010134）资助项目.

A New Serratane Triterpenoid from Lycopodiella cernua

Jin Yu^a,c, Huang Zhengwan^a,c, Huang Yingna^b, Xu Yingting^a,c, Yan Jian^d, Yang Jie^b, Zhou Zhongyu^a, Wei Xiaoyi^a

a Key Laboratory of Plant Resources Conservation and Sustainable Utilization&Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650;
b Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515;
c University of Chinese Academy of Sciences, Beijing 100049;
d Key Laboratory of Agro-environment in the Tropics, Ministry of Agriculture and Rural Affairs;Guangdong Provincial Key Laboratory of Eco-Circular Agriculture;Guangdong Engineering Research Centre for Modern Eco-Agriculture;College of Natural Resources and Environment, South China Agricultural University, Guangzhou 510642

Received:2020-04-03 Revised:2020-04-27 Published:2020-06-01
Supported by:
Project supported by the National Natural Science Foundation of China (No. 31970376), the Youth Innovation Promotion Association, Chinese Academy of Sciences (No. 2016310), and the Guangzhou Science and Technology Program (No. 201904010134).

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摘要/Abstract

利用多种色谱分离方法对垂穗石松的化学成分进行研究，从其全株的乙醇提取物中分离得到2个化合物，用MS和NMR等多种现代波谱技术确定了化合物的结构，经鉴定分别为3β，14α，15α，21β-四羟基-15-（3'-甲氧基-4'-羟基苯甲酰）-千层塔烷（1）和16-酮基-3β，21α-二羟基-14-千层塔烯（2）.其中化合物1为新化合物，2个化合物均为首次从小石松属植物分离.

关键词: 垂穗石松, 千层塔三萜, 抗甲型流感病毒

Two serratane triterpenoids, 3β,14α,15α,21β-tetrahydroxyserrat-15-(3'-methoxyl-4'-hydroxybenzoate) (1) and 16-oxoserrat-14-en-3β,21α-diol (2), were isolated from the whole plant of Lycopodiella cernua. Compound 1 was a new one. The structures of these compounds were identified by analysis of spectral data. These two compounds were isolated from Lycopodiella genus for the first time.

Key words: Lycopodiella cernua, serratane triterpenoid, anti-influenza A virus

引用此文

金玉, 黄政皖, 黄英娜, 徐莺婷, 颜健, 杨洁, 周忠玉, 魏孝义. 垂穗石松中一个新的千层塔三萜[J]. 有机化学, 2020, 40(8): 2531-2534.

Jin Yu, Huang Zhengwan, Huang Yingna, Xu Yingting, Yan Jian, Yang Jie, Zhou Zhongyu, Wei Xiaoyi. A New Serratane Triterpenoid from Lycopodiella cernua[J]. Chinese Journal of Organic Chemistry, 2020, 40(8): 2531-2534.

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垂穗石松中一个新的千层塔三萜

A New Serratane Triterpenoid from Lycopodiella cernua

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