有机化学 ›› 2021, Vol. 41 ›› Issue (4): 1607-1613.DOI: 10.6023/cjoc202008035 上一篇    下一篇

研究论文

氮杂环卡宾(NHC)/银(I)共催化合成2-氧代-2-芳乙基芳甲酸酯

成立1, 王文蓉1, 孙玉倩1, 李团结1,* , 于晨侠1, 姚昌盛1,*()   

  1. 1 江苏师范大学化学与材料科学学院 江苏省功能材料绿色合成重点实验室 江苏徐州 221116
  • 收稿日期:2020-08-20 修回日期:2020-10-13 发布日期:2020-12-24
  • 通讯作者: 李团结, 姚昌盛
  • 基金资助:
    国家自然科学基金(2177020721); 国家自然科学基金(21871113); 江苏高等学校自然科学基金(17KJA150003)

N-Heterocyclic Carbene (NHC)/Ag(I) Co-catalyzed Synthesis of 2-Oxo-2-arylethyl Aryl Formates

Li Cheng1, Wenrong Wang1, Yuqian Sun1, Tuanjie Li1,* , Chenxia Yu1, Changsheng Yao1,*()   

  1. 1 Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou, Jiangsu 221116
  • Received:2020-08-20 Revised:2020-10-13 Published:2020-12-24
  • Contact: Tuanjie Li, Changsheng Yao
  • About author:
    * Corresponding authors. E-mail: ;
  • Supported by:
    National Science Foundation of China(2177020721); National Science Foundation of China(21871113); Natural Science Foundation of the Jiangsu Higher Education Institution(17KJA150003)

在氮杂环卡宾(NHC)/银(I)的共催化下, 以芳醛和(溴乙炔)苯及其衍生物为原料实现了2-氧代-2-芳乙基芳甲酸酯高效合成. 该方法具有底物范围广、原料简单易得、操作简便等优点, 为α-酰氧基羰基衍生物的简捷合成提供了新思路.

关键词: 氮杂环卡宾(N-heterocyclic carbene, NHC), 银(I), 共催化, α-酰氧基酮

An N-heterocyclic carbene (NHC)/Ag(I) co-catayzed efficient synthesis of 2-oxo-2-arylethyl aryl formates was realized by the reaction of aryl aldehydes with (bromoethynyl)benzenes. This method features broad substrate scope, ready availability of starting materials and operational simplicity, which gives an alternative access to α-acyloxycarbonyl derivatives.

Key words: N-heterocyclic carbene (NHC), Ag(I), co-catalysis, α-acyloxycarbonyl derivatives