有机化学 ›› 2004, Vol. 24 ›› Issue (5): 485-497. 上一篇    下一篇

综述与进展

双膦酸及其酯类化合物的合成研究进展

吴明书, 陈茹玉*, 黄有   

  1. 南开大学元素有机化学研究所 元素有机化学国家重点实验室 天津 300071
  • 收稿日期:2003-05-19 修回日期:2003-09-05 接受日期:2003-10-17 发布日期:2022-09-20

Progress in Synthesis of Bisphosphonic(ate) Analogues

WU, Ming-Shu, CHEN, Ru-Yu*, HUANG, You   

  1. Institute of Elemento-Organic Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071
  • Received:2003-05-19 Revised:2003-09-05 Accepted:2003-10-17 Published:2022-09-20
  • Contact: *E-mail: hyou@nankai.edu.cn

综述了双膦酸及其酯类化合物的最新合成研究进展:(1) α-羟基取代的双膦酸及其酯;(2) α-氨基酸取代的双膦酸及其酯;(3)α-卤素取代的双膦酸及其酯;(4)烷基取代的双膦酸及其酯;(5) α-杂原子取代的双膦酸及其酯.

关键词: 双磷酸及其酯, 合成, 进展

This review is classified into five parts as follows: (1) α-hydroxy substituted bisphosphonic(ate) analogues, (2) α-amino substituted bisphosphonic(ate) analogues, (3) α-halogen substitutedbisphosphonic(ate) analogues, (4) α-alkyl substituted bisphosphonic(ate) analogues, (5) α-heteroatom substituted bisphosphonic(ate) analogues, giving a survey of progress in the synthesis of bisphosphonic and (ate) analogues with 122 references.

Key words: bisphosphonic(ate) analogue, synthesis, progress