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有机化学 ›› 2004, Vol. 24 ›› Issue (9): 1060-1063. 上一篇    下一篇

研究论文

网胰藻Hydroclathrus clathratus的化学成分研究

李筱玲, 徐石海*, 曾向潮, 郭书好, 何冬红, 杨凯   

  1. 暨南大学化学系 广州 510632
  • 收稿日期:2003-06-23 修回日期:2004-02-10 接受日期:2004-03-24 发布日期:2022-09-20
  • 基金资助:
    国家863青年科学基金(No. 2001AA628100)、国家自然科学基金(No. 2002001)、广东省自然科学基金(No. 000720)资助项目.

Studies on the Chemical Constituents of the Algae Hydroclathrus clathratus

LI Xiao-Ling, XU Shi-Hai*, ZENG Xiang-Chao, GUO Shu-Hao, HE Dong-Hong, YANG Kai   

  1. Department of Chemistry, Jinan University, Guangzhou 510632
  • Received:2003-06-23 Revised:2004-02-10 Accepted:2004-03-24 Published:2022-09-20
  • Contact: * E-mail: txush@jnu.edu.cn

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报道从中国南海网胰藻Hydroclathrus clathratus中分离得到3个单体化合物,经过MS, IR, 1H NMR, 13C NMR (DEPT), HMQC和HMBC等波谱技术鉴定为:(6R,7aS)-6-羟基-4,4,7a-三甲基-2,4,5,6,7,7a-六氢苯并呋喃-2-酮(1), 1-(2-脱氧-β-D-呋喃核糖)-5-甲基-1,2,3,4-四氢嘧啶-2,4-二酮(2),尿嘧啶(3),并通过X射线单晶衍射实验确定化合物1的立体结构,其中化合物1是首次从自然界中分离得到.

关键词: 海藻, Hydroclathrus clathratus, 化学成分, (6R,7aS)-6-羟基-4,4,7a-三甲基-2,4,5,6,7,7a-六氢苯并呋喃-2-酮

Three compounds have been isolated from the algae Hydroclathrus clathratus collected from the South China Sea. Their structures were established as (6R,7aS)-6-hydroxy-4,4,7a-trimethyl-2,4,5,6,7,7a-hexahydrobenzofuran-2-one (1), 1-(2-deoxy-β-D-ribofuranosyl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (2) and uracil (3) by MS, IR, NMR spectra and X-ray diffraction analysis. Compound 1 was isolated from natural resources for the first time.

Key words: algae, Hydroclathrus clathratus, chemical constituent, (6R,7aS)-6-hydroxy-4,4,7a-trimethyl-2,4,5,6,7,7a-hexahydrobenzofuran-2-one