烷烃C—H键的区域选择性烯丙基化

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米一曼, 黄学良^*()

Yiman Mi, Xueliang Huang()

College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081

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米一曼, 黄学良. 烷烃C—H键的区域选择性烯丙基化[J]. 有机化学, 2023, 43(1): 359-361.

Yiman Mi, Xueliang Huang. Selective C—H Allylation of Alkanes[J]. Chinese Journal of Organic Chemistry, 2023, 43(1): 359-361.

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图1. 含有烯丙基季碳(sp3)的生物活性分子和药物分子

Figure 1. Selected examples of bioactive and drug molecules containing allylic quaternary sp3-carbon

图2. 区域选择性烷烃C—H键的烯丙基化

Figure 2. Site-selective 3° C—H insertion of alkanes for allylic quaternary sp3-carbon formation

图3. 转化以及合成药物衍生物

Figure 3. Further transformations and application toward medicinally relevant compounds

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