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2012 , Vol. 32 >Issue 05: 825 - 833

DOI: https://doi.org/10.6023/cjoc1110053

综述与进展

亚砜亚胺类化合物的合成及应用研究进展

  • 王娅娅 ,
  • 洪学传 ,
  • 邓子新
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  • 武汉大学药学院 组合生物合成与新药发现教育部重点实验室 武汉 430071

收稿日期: 2011-10-05

  修回日期: 2011-11-30

  网络出版日期: 2011-12-14

基金资助

植物化学与西部植物资源持续利用国家重点实验室开放课题(No. P2010-KF10)、高等学校博士学科点专项科研基金(No. 20110141120017)、国家自然科学基金(No. 81102357)资助项目.

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Progress in the Synthesis and Application of Sulfoximines

  • Wang Yaya ,
  • Hong Xuechuan ,
  • Deng Zixin
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  • Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071

Received date: 2011-10-05

  Revised date: 2011-11-30

  Online published: 2011-12-14

Supported by

Project supported by the Fund of State Key Laboratory of Phytochemistry and Plant Resources in West China (No. P2010-KF10), the Specialized Research Fund of the Doctoral Program of Higher Education (No. 20110141120017), and the National Natural Science Foundation of China (No. 81102357).

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摘要

亚砜亚胺(Sulfoximine)类化合物是一类重要的杂原子取代化合物, 引起了人们的广泛关注. 综述了近十年来亚砜亚胺类化合物的研究进展, 包括该类化合物的合成及在不对称催化领域中的应用、含有亚砜亚胺的生物活性小分子合成和天然产物全合成. 并对发展趋势和应用前景做了展望.

关键词： 亚砜亚胺; 合成; 应用; 不对称催化; 全合成

本文引用格式

王娅娅 , 洪学传 , 邓子新 . 亚砜亚胺类化合物的合成及应用研究进展[J]. 有机化学, 2012 , 32(05) : 825 -833 . DOI: 10.6023/cjoc1110053

Abstract

Sulfoximines are a very important class of heteroatom substitutional compounds and have attracted considerable interest. This review deals with methods for the synthesis of sulfoximines and their applications in catalytical asymmetric synthesis, bioactive small molecules synthesis and total synthesis of natural products. The developing trend and prospects for future application of sulfoximines compound are discussed.

Key words： sulfoximines; synthesis; application; asymmetric catalysis; total synthesis

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