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2012 >Issue 03: 608 - 611

DOI: https://doi.org/10.6023/cjoc1108011

研究简报

新型3-取代(硫)色满-4-酮衍生物的合成及其结构表征

  • 吴利欢 ,
  • 郭海福 ,
  • 黄新仪 ,
  • 吴瑞芬
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  • 肇庆学院化学化工学院 肇庆 526060

收稿日期: 2011-08-01

  修回日期: 2011-09-18

  网络出版日期: 2012-03-24

基金资助

肇庆市科技创新计划(No. 2009G12)和广东省自然科学基金(No. 07010338)资助项目.

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Synthesis and Structure Characterization of Novel 3-Substituted-(thio)chroman-4-one Derivatives

  • Wu Lihuan ,
  • Guo Haifu ,
  • Wang Xinyi ,
  • Wu Ruifen
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  • School of Chemistry and Chemical Engineering, Zhaoqing University, Zhaoqing 526060

Received date: 2011-08-01

  Revised date: 2011-09-18

  Online published: 2012-03-24

Supported by

Project supported by the Scientific and Technological Innovation of Zhaoqing City (No. 2009G12) and the Natural Science Foundation of Guangdong Province (No. 07010338).

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摘要

以取代或未取代(硫)色满酮和芳香醛为原料, 在氢氧化钠催化下, 分别采用常规溶剂法与无溶剂研磨法两种不同方式, 合成一系列新型的3-取代(硫)色满-4-酮衍生物3a～3l. 无溶剂研磨法具有操作简便、反应条件温和、反应时间短、对环境友好等优点. 所合成的标题化合物的结构通过 IR, 1H NMR, 13C NMR 和MS 进行了鉴定和表征.

关键词： 色满酮; 无溶剂; 研磨法

本文引用格式

吴利欢 , 郭海福 , 黄新仪 , 吴瑞芬 . 新型3-取代(硫)色满-4-酮衍生物的合成及其结构表征[J]. 有机化学, 2012 , (03) : 608 -611 . DOI: 10.6023/cjoc1108011

Abstract

A series of novel 3-substituted-(thio)chroman-4-one derivatives 3a～3l were synthesized by the condensation of substituted (unsubstituted)-(thio)chromanone with aromatic aldehydes in the presence of sodium hydroxide, via two different methods of conventional solvent method and solvent-free grinding method which has advantages of simple work-up procedure, shorter reaction time, milder conditions and environ-mental friendliness. The structures of the title compounds 3a～3l were characterized by IR, 1H NMR, 13C NMR and MS techniques.

Key words： chromanone; solvent-free; grinding

参考文献

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