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2012 , Vol. 32 >Issue 04: 786 - 789

DOI: https://doi.org/10.6023/cjoc1107201

研究简报

丙酮肟氧化偶联合成2,3-二甲基-2,3-二硝基丁烷反应的研究

  • 张胜建 ,
  • 赵迎宪 ,
  • 张洪
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  • 浙江大学宁波理工学院 宁波 315100

收稿日期: 2011-07-20

  修回日期: 2011-11-28

  网络出版日期: 2012-04-24

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Synthesis of 2,3-Dimethyl-2,3-dinitrobutane by Oxidative Coupling of Acetone Oxime

  • Zhang Shengjian ,
  • Zhao Yingxian ,
  • Zhang Hong
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  • Ningbo Institute of Technology, Zhejiang University, Ningbo 315100

Received date: 2011-07-20

  Revised date: 2011-11-28

  Online published: 2012-04-24

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摘要

以丙酮肟为原料, 在改性TS-1(钛硅分子筛)催化剂催化下, 可用H2O2 氧化偶联合成2,3-二甲基-2,3-二硝基丁烷(DMNB). 在此基础上以丙酮为原料, 在改性TS-1 催化剂催化下, 一锅法进行丙酮氨肟化和氧化偶联反应可制备收率43.2%的DMNB. 该方法简便易操作, 操作安全. 产物结构经1H NMR, 13C NMR 表征.

关键词： 丙酮肟; 氧化偶联; 双氧水; 2,3-二甲基-2,3-二硝基丁烷; 改性TS-1 催化剂

本文引用格式

张胜建 , 赵迎宪 , 张洪 . 丙酮肟氧化偶联合成2,3-二甲基-2,3-二硝基丁烷反应的研究[J]. 有机化学, 2012 , 32(04) : 786 -789 . DOI: 10.6023/cjoc1107201

Abstract

2,3-Dimethyl-2,3-dinitrobutane (DMNB) was prepared by oxidative coupling of acetone oxime with H2O2 over the modified TS-1 catalyst. In one-pot operation, the ammoximation of acetone followed by catalytic oxidative coupling over TS-1 produced the DMNB with yield of 43.2%. The operation is simple and safe. The structures of products were identified by 1H NMR and 13C NMR spectra.

Key words： acetone oxime; oxidative coupling; hydrogen peroxide; 2,3-dimethyl-2,3-dinitrobutane; modified TS-1 catalyst

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