2,3,8,9-四氢吡啶并[2,3-d:6,5-d']二嘧啶-4,6-二酮衍生物的合成
收稿日期: 2012-08-31
修回日期: 2012-09-19
网络出版日期: 2012-09-26
基金资助
北京理工大学研究生科技创新专项计划(No. 2011CX0436)资助项目.
Synthesis of 2,3,8,9-Tetrahydropyrido[2,3-d:6,5-d']dipyrimidine-4,6-diones
Received date: 2012-08-31
Revised date: 2012-09-19
Online published: 2012-09-26
Supported by
Project supported by the Science and Technology Innovation Program of Beijing Institute of Technology (No. 2011CX0436).
杨留攀 , 李加荣 , 柴洪新 , 袁洪 , 张奇 , 史大昕 . 2,3,8,9-四氢吡啶并[2,3-d:6,5-d']二嘧啶-4,6-二酮衍生物的合成[J]. 有机化学, 2013 , 33(01) : 174 -177 . DOI: 10.6023/cjoc201208039
2,3,8,9-Tetrahydropyrido[2,3-d:6,5-d']dipyrimidine-4,6-diones were synthesized by using malononitrile, ortho-triethyl and pyridine as starting materials in three steps reaction including cyclization, ammonolysis and reaction with ketones under the catalysis of sodium methoxide. The structures of the products were confirmed by NMR, IR, ESI and elemental analysis.
Key words： pyridodipyrimidinediones; heterocycle; synthesis
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