二乙酸碘苯促进芳基酮烯醇硅醚的氯化反应
收稿日期: 2015-11-19
修回日期: 2015-12-30
网络出版日期: 2016-02-01
基金资助
国家自然科学基金(Nos.21362033,21502154)资助项目.
Diacetoxyiodobenzene Promoted Chlorination of Silyl Enol Ether of Aryl Ketones
Received date: 2015-11-19
Revised date: 2015-12-30
Online published: 2016-02-01
Supported by
Project supported by the National Natural Science Foundation of China (Nos. 21362033, 21502154).
陈小伟 , 种思颖 , 杜刚刚 , 黄丹凤 , 王克虎 , 苏瀛鹏 , 胡雨来 . 二乙酸碘苯促进芳基酮烯醇硅醚的氯化反应[J]. 有机化学, 2016 , 36(5) : 1028 -1033 . DOI: 10.6023/cjoc201511041
A series of α-chloroketones were obtained from silyl enol ethers of aryl ketones using trimethylchlorosilane as chlorine source and diacetoxyiodobenzene as promoter. The reaction occurs under mild condition yielding the product in moderate to good yields, and has the potential possibility for the synthesis of α-bromoketone by using trimethyl bromosilane as bromine source.
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