ZnAl-BrO3--LDHs/KBr溴源在苯胺类化合物选择性氧化溴代的应用
Selective Oxidative Bromination of Anilines Using Potassium Bromide and ZnAl-BrO3--LDHs
Received date: 2017-05-11
Revised date: 2017-07-07
Online published: 2017-09-08
王力耕 , 陈璐焌 , 章华隆 , 余琴 . ZnAl-BrO3--LDHs/KBr溴源在苯胺类化合物选择性氧化溴代的应用[J]. 有机化学, 2017 , 37(12) : 3186 -3190 . DOI: 10.6023/cjoc201705017
The oxidative bromination of anilines was realized with ZnAl-BrO3--LDHs/KBr as the bromine source at ambient temperature in acidic medium (AcOH/H2O). High yields of monobrominated or polybrominated anilines were achieved for a wide range of anilines. Both the substrate structure and the reaction conditions will significantly influence the reaction selectivity. The use of inexpensive reagents, environmentally benign and operationally simple process, and excellent yields make it a good alternative to the synthesis of bromoanilines.
Key words： anilines; halogenation; selectivity; aromatic substitution
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