碳正离子介导的二氢喹啉的氧化碳氢炔基化
Trityl Ion-Mediated Oxidative C—H Alkynylation of 1, 2-Dihydroquinolines
Received date: 2018-03-01
Revised date: 2018-03-16
Online published: 2018-04-13
刘子强 , 赵冉 , 贺妮 , 李伟 . 碳正离子介导的二氢喹啉的氧化碳氢炔基化[J]. 有机化学, 2018 , 38(5) : 1261 -1266 . DOI: 10.6023/cjoc201803001
An efficient synthesis of α-substituted 1, 2-dihydroquinoline compounds through the oxidative C—H functionalization of N-acyl-dihydroquinoline with diverse organoboron reagents mediated by triphenylcarbium perchlorate (Ph3CClO4) is reported. The reaction exhibits good functional group tolerance, allowing for C—H alkynylation and alkenylation proceeding smoothly in good yields.
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