氧杂蒽与亚磺酸钠的电化学氧化C(sp3)—H磺酰化反应
收稿日期: 2022-07-05
修回日期: 2022-07-29
网络出版日期: 2022-09-15
基金资助
国家自然科学基金(51878326); 国家自然科学基金(21861027); 国家自然科学基金(22161030); 国家自然科学基金(21901100); 江西省自然科学基金(20212ACB203007); 江西省自然科学基金(20204BCJ23010); 江西省自然科学基金(20202ACBL216017); 江西省自然科学基金(20212AEI91002); 江西省自然科学基金(20202ACB203002); 江西省教育厅自然科学基金(GJJ210906); 江西省教育厅自然科学基金(GJJ210909)
Electrochemical Oxidative C(sp3)—H Sulfonylation of Xanthenes with Sodium Sulfinates
Received date: 2022-07-05
Revised date: 2022-07-29
Online published: 2022-09-15
Supported by
National Natural Science Foundation of China(51878326); National Natural Science Foundation of China(21861027); National Natural Science Foundation of China(22161030); National Natural Science Foundation of China(21901100); Natural Science Foundation of Jiangxi Province(20212ACB203007); Natural Science Foundation of Jiangxi Province(20204BCJ23010); Natural Science Foundation of Jiangxi Province(20202ACBL216017); Natural Science Foundation of Jiangxi Province(20212AEI91002); Natural Science Foundation of Jiangxi Province(20202ACB203002); Natural Science Foundation of Jiangxi Provincial Education Department(GJJ210906); Natural Science Foundation of Jiangxi Provincial Education Department(GJJ210909)
危斌 , 周子龙 , 秦景灏 , 严泽宇 , 郭嘉程 , 雷澍 , 谢叶香 , 欧阳旋慧 , 宋仁杰 . 氧杂蒽与亚磺酸钠的电化学氧化C(sp3)—H磺酰化反应[J]. 有机化学, 2023 , 43(1) : 186 -194 . DOI: 10.6023/cjoc202207012
A direct electrochemical sulfonylation of C(sp3)—H bonds of xanthenes with sodium sulfinates was studied. A wide variety of 9-(arylsulfonyl)-9H-xanthenes and 9-(alkylsulfonyl)-9H-xanthenes were constructed in a single step at room temperature. This reaction proceeded through a radical pathway and a new C—S bond was formed under this electrochemical sulfonylation transformation. The significant advantages of this strategy include transition metal- and additional oxidant-free, mild reaction conditions, operational simplicity, broad substrate scope and excellent functional group tolerance.
Key words： electrooxidation; sulfonylation; xanthene; sodium sulfinate
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