灵芝杂萜的全合成研究进展
收稿日期: 2024-09-27
修回日期: 2024-12-17
网络出版日期: 2024-12-27
基金资助
陕西省自然科学研究计划(2024JC-YBMS-641); 国家自然科学基金(21901211); 国家自然科学基金(81903466); 国家自然科学基金(22471221)
Advances in the Total Synthesis of Ganoderma Meroterpenoids
Received date: 2024-09-27
Revised date: 2024-12-17
Online published: 2024-12-27
Supported by
Natural Science Research Program of Shaanxi Province(2024JC-YBMS-641); National Natural Science Foundation of China(21901211); National Natural Science Foundation of China(81903466); National Natural Science Foundation of China(22471221)
高志宇 , 路雪娜 , 李奕晴 , 任丽 , 郝宏东 . 灵芝杂萜的全合成研究进展[J]. 有机化学, 2025 , 45(3) : 814 -836 . DOI: 10.6023/cjoc202409039
Ganoderma meroterpenoids are natural products containing aromatic ring with terpenoid fragments. In recent years, numerous Ganoderma meroterpenoids with novel carbon skeleton and different oxidation state were discovered by Chinese scientists. Among these natural product, anti-renal fibrosis, anti-inflammatory, anti-Alzheimer’s disease, antioxidant, hypoglycemic activities and calcium channel inhibitory were reported. Therefore, these natural products have attracted attention from pharmacology and synthetic chemists. The progress on the total synthesis of Ganoderma meroterpenoids is summarized.
Key words： Ganoderma; meroterpenoids; total synthesis
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