Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (01): 1-17.DOI: 10.6023/cjoc201208032 Previous Articles     Next Articles

Reviews

不对称有机催化Michael加成/半缩醛胺化/酰亚胺正离子环化串联反应研究进展

陈杰, 刘钦, 戴小鸯, 聂凛凛, 房辉辉, 吴小余   

  1. 上海大学化学系 上海 200444
  • 收稿日期:2012-08-28 修回日期:2012-09-12 发布日期:2012-09-18
  • 通讯作者: 吴小余 E-mail:wuxy@shu.edu.cn
  • 基金资助:

    国家自然科学基金(Nos. 20802043, 210072125)资助项目.

Progress in Asymmetric Organocatalyzed Michael Addition/Hemi-aminoacetalization/Acylimminium-Cyclization Cascade Reactions

Chen Jie, Liu Qin, Dai Xiaoyang, Nie Linlin, Fang Huihui, Wu Xiaoyu   

  1. Department of Chemistry, Shanghai University, Shanghai 200444
  • Received:2012-08-28 Revised:2012-09-12 Published:2012-09-18
  • Supported by:

    Project supported by the the National Natural Science Foundation of China (Nos. 20802043, 21072125).

During the last decades along with the development of asymmetric organocatalysis, tremendous achievements have been made in asymmetric organocatalytic domino or cascade reactions. Herein, the examples of domino or cascade reactions based on asymmetric organocatalyzed Michael addition are described. More specifically, this review aims to cover and discuss the hemi-aminoacetalyzation/acylimminium-cyclization initiated by Michael addition, and the application of this type of reactions in the synthesis of alkaloids.

Key words: organocatalysis, cascade reaction, N-containing multi cycles, alkaloid