Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (5): 1316-1322.DOI: 10.6023/cjoc201903009 Previous Articles     Next Articles

Special Issue: 碳氢活化合辑2018-2019



张振雷, 钱朋, 查正根   

  1. 中国科学技术大学化学与材料学院 合肥 230026
  • 收稿日期:2019-03-05 修回日期:2019-03-26 发布日期:2019-04-19
  • 通讯作者: 张振雷, 查正根;
  • 基金资助:


Copper-Catalyzed Aerobic Oxidative Coupling of Aromatic Sulfonyl Hydrazides with Amines:A New Access to Aromatic Sulfonamides

Zhang Zhenlei, Qian Peng, Zha Zhenggen   

  1. School of Chemistry and Materials Science, University of Science and Technology of China, Hefei 230026
  • Received:2019-03-05 Revised:2019-03-26 Published:2019-04-19
  • Contact: 10.6023/cjoc201903009;
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21672200, 21472177).

A copper(Ⅱ)-catalyzed aerobic oxidative coupling of aromatic sulfonyl hydrazides with amines for the synthesis of aromatic sulfonamides was described. In contrast to previously described methods, this reaction employs copper/O2 as the catalytic system, and generates N2 as the only byproduct, which provides an environmentally benign synthetic route for aromatic sulfonamides.

Key words: copper catalysis, sulfonyl hydrazide, sulfonamide