Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (8): 2476-2482.DOI: 10.6023/cjoc202002042 Previous Articles     Next Articles


李怀贵, 杨澎, 许峥, 杜正银, 傅颖   

  1. 西北师范大学化学化工学院 兰州 730070
  • 收稿日期:2020-02-29 修回日期:2020-05-10 发布日期:2020-05-20
  • 通讯作者: 杜正银, 傅颖;
  • 基金资助:

Cu-Catalyzed Direct Arylation of Benzothiazoles with Diaryliodonium Salts

Li Huaigui, Yang Peng, Xu Zheng, Du Zhengyin, Fu Ying   

  1. College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070
  • Received:2020-02-29 Revised:2020-05-10 Published:2020-05-20
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Nos. 21262028, 21762039, 21762040).

Diaryliodonium salts have low toxicity and good stability, and their mediated reactions often have advantages of mild reaction conditions and high selectivity. They have received extensive attention and have been widely used as arylating agents in organic synthesis. A simple and efficient method for the synthesis of 2-arylbenzothiazole derivatives via copper-catalyzed C-H direct arylation of benzothiazoles with diaryliodonium salts as electrophilic arylating reagents was developed. This method shows wide range of substrates, good group tolerance, simple operation and high product yields.

Key words: benzothiazole, arylation, diaryliodonium salt, cross coupling, C-H activation