Structures, synthesis and biological activity of new constituents from traditional Chinese medicine

Abstract

Thirty compounds were isolated from the traditional Chinese medicine "Gao-Ben", which consists of three species of Ligusticum and Conioselinum genus. The structure and stereochemistry of several new compounds were established by spectral and chemical evidence. Preliminary pharmacological tests showed some isolates have significant biological activities. The total synthesis of a few bioactive compounds isolated from "Gao-Ben" and their analogues were described.

Key words: ACTIVITY, LIGUSTICUM, CHEMICAL COMPOSITION

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YU DEQUAN. Structures, synthesis and biological activity of new constituents from traditional Chinese medicine "Gao-Ben"[J]. Chin. J. Org. Chem., 1997, 17(1): 24-27.

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常用中药藁本中新化合物的结构, 合成及活性研究

Structures, synthesis and biological activity of new constituents from traditional Chinese medicine "Gao-Ben"

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