Chin. J. Org. Chem. ›› 1998, Vol. 18 ›› Issue (1): 11-19. Previous Articles     Next Articles

Original Articles

在非水介质中进行酶促反应的几个重要问题

田桂玲;邢国文;叶蕴华   

  1. 北京大学化学与分子工程学院
  • 发布日期:1998-02-25

Some important problems of enzymatic reactions in non-aqueous media

TIAN GUILING;XING GUOWEN;YE YUNHUA   

  • Published:1998-02-25

Recent progress of enzymatic reaction in organic solvents was comprehensively discussed. Activities and stereoselectivities of enzymes are depended on the properties of solvents. Their catalytic activities and thermostabilities are effected strongly by the essential water in organic solvents. The dramatic enhancement of enzymatic activity in organic solvents by the presence of simple non-buffer salts in the lyophilized enzyme was also discussed. Some proteases have shown their catalytic activities in eutectic mixtures of substrates and have been used to synthesize various model oligopeptides.

Key words: FUSE ELEMENTS, NON-AQUEOUS SOLUTION, ENZYMATIC, BIOLOGICAL ACTIVITY, POLARITY, STEREOSELECTIVITY, MICELLAR SOLUTION, MEDIA, BUFFER SOLUTION, ENZYME

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